2-AMINO-N-(4-METHOXY-PHENYL)-BENZAMIDE

Base Information

• Chemical Name: 2-AMINO-N-(4-METHOXY-PHENYL)-BENZAMIDE
• CAS No.: 20878-54-0
• Molecular Formula: C14H14N2O2
• Molecular Weight: 242.277
• Hs Code.: 2924299090
• Mol file: 20878-54-0.mol

Synonyms:2-Amino-N-(4-methoxy-phenyl)-benzamide;Anthranilsaeure-p-anisidid;4'-Methoxyanthranilanilide;Anthranilic acid 4-anisidide;(2-aminophenyl)-N-(4-methoxyphenyl)carboxamide;N-(4-methoxyphenyl)-2-aminobenzamide;anthranilic acid p-anisidide;

Chemical Property of 2-AMINO-N-(4-METHOXY-PHENYL)-BENZAMIDE

Chemical Property:

• Vapor Pressure: 4.83E-05mmHg at 25°C
• Boiling Point: 349°Cat760mmHg
• Flash Point: 164.9°C
• PSA: 64.35000
• Density: 1.245g/cm³
• LogP: 3.18390

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-N-(4-methoxyphenyl)benzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-N-(4-METHOXY-PHENYL)-BENZAMIDE

There total 12 articles about 2-AMINO-N-(4-METHOXY-PHENYL)-BENZAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

isatoic anhydride (118-48-9) + 4-methoxy-aniline (104-94-9) → 2-amino-N-(4-methoxyphenyl)benzamide (20878-54-0)

Guidance literature:

In water; at 80 ℃; for 9h; Large scale;

Reference yield: 82.0%

2-nitro-N-(4-methoxyphenyl)benzamide (22979-83-5) → 2-amino-N-(4-methoxyphenyl)benzamide (20878-54-0)

Guidance literature:

With tetrahydroxydiboron; 5%-palladium/activated carbon; water; In acetonitrile; at 50 ℃; for 24h;

DOI:10.1016/j.tet.2017.05.056

Reference yield: 71.0%

4-methoxy-aniline (104-94-9) + 2-carbomethoxyaniline (134-20-3) → 2-amino-N-(4-methoxyphenyl)benzamide (20878-54-0)

Guidance literature:

4-methoxy-aniline; With trimethylaluminum; In dichloromethane; toluene; at 20 ℃; for 45h;

2-carbomethoxyaniline; In dichloromethane; toluene; Heating;

DOI:10.1021/jo060070+

upstream raw materials:

isatoic anhydride

4-methoxy-aniline

2-carbomethoxyaniline

2-nitro-N-(4-methoxyphenyl)benzamide

Downstream raw materials:

3-(4-methoxy-phenyl)-2,3-dihydro-1H-quinazolin-4-one

2-(2,2-Dicyano-vinylamino)-N-(4-methoxy-phenyl)-benzamide

(E)-2-Cyano-3-[2-(4-methoxy-phenylcarbamoyl)-phenylamino]-acrylic acid ethyl ester

N-(2-amino-benzyl)-p-anisidine