2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-

Base Information

Chemical Name:2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-
CAS No.:56948-73-3
Molecular Formula:C12H12F3NO2
Molecular Weight:259.2244
Hs Code.:2933790090
DSSTox Substance ID:DTXSID00972399
ChEMBL ID:CHEMBL104328

Synonyms:56948-73-3;BRN 1541281;2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-;5-Hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-2-pyrrolidinone;5-hydroxy-1-methyl-5-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one;CHEMBL104328;SCHEMBL11813845;5-hydroxy-1-methyl-5-(m-trifluoromethylphenyl)pyrrolidone;DTXSID00972399;LS-138858

Suppliers and Price of 2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-

Chemical Property:

Vapor Pressure:9.42E-06mmHg at 25°C
Boiling Point:358.2°Cat760mmHg
Flash Point:170.4°C
PSA：40.54000
Density:1.368g/cm³
LogP:2.04060
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:259.08201311
Heavy Atom Count:18
Complexity:345

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)CCC1(C2=CC(=CC=C2)C(F)(F)F)O

Technology Process of 2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-

There total 3 articles about 2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1121-07-9
N-methylsuccinimide

: 401-78-5
3-bromo-1-trifluoromethylbenzene

: 56948-73-3
5-hydroxy-1-methyl-5-(m-trifluoromethylphenyl)pyrrolidone

Guidance literature:: With magnesium; Yield given. Multistep reaction; 1.) Et₂O, reflux, 1 h, 2.) Et₂O, C₆H₆, reflux, 4 h;
DOI:10.1021/jm00379a007