(+/-)-Meso-corydaline

Base Information

Chemical Name:(+/-)-Meso-corydaline
CAS No.:6901-07-1
Molecular Formula:C22H27NO4
Molecular Weight:0
Hs Code.:
UNII:9563O955PJ,MI57Q9014K
Nikkaji Number:J34.212B
Wikidata:Q105291934
Mol file:6901-07-1.mol

Synonyms:(+/-)-Meso-corydaline;DL-Mesocorydaline;Mesocorydaline;(+/-)-Mesocorydaline;DL-Mesocorydaline [MI];Mesocorydaline, (+/-)-;D-Mesocorydaline;UNII-MI57Q9014K;(+)-Mesocorydaline;D-Mesocorydaline [MI];MI57Q9014K;Mesocorydaline, (+)-;6018-36-6;9563O955PJ;(13RS,13Ars)-5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo(a,g)-quinolizine;6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13R,13aR)-rel-;6901-07-1;(13R,13aR)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo(a,g)-quinolizine;6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13R,13aR)-;6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-, (13R-cis)-;UNII-9563O955PJ;AKOS000278015;13abeta-Berbine, 2,3,9,10-tetramethoxy-13beta-methyl-;13A.BETA.-BERBINE, 2,3,9,10-TETRAMETHOXY-13.BETA.-METHYL-

Suppliers and Price of (+/-)-Meso-corydaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of (+/-)-Meso-corydaline

Chemical Property:

PSA：40.16000
LogP:3.87540
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:369.19400834
Heavy Atom Count:27
Complexity:503

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC
Isomeric SMILES:C[C@H]1[C@@H]2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC

Technology Process of (+/-)-Meso-corydaline

There total 15 articles about (+/-)-Meso-corydaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 2-<2,3-dimethoxy-6-(1'-trimethylsilylethyl)benzyl>-6,7-dimethoxy-3,4-dihydroisoquinolinium perchlorate

: 518-69-4,6018-35-5,6018-36-6,6018-38-8,6901-07-1,71213-90-6
mesocorydaline

: 6018-35-5
trans-(+-)-5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine

Guidance literature:: In methanol; for 24h; Irradiation;

Reference yield:

: 518-69-4,6018-35-5,6018-36-6,6018-38-8,6901-07-1,71213-90-6
mesocorydaline

: 6018-35-5
trans-(+-)-5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine

Guidance literature:: With ethanol; sulfuric acid; zinc; at 20 ℃;

Reference yield:

: 139577-08-5
N,N-dimethyl-N-(1-(3',4'-dimethoxyphenyl)ethyl)amine

: 518-69-4,6018-35-5,6018-36-6,6018-38-8,6901-07-1,71213-90-6
mesocorydaline

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) BuLi / 1.) THF, 0 deg C, 1 h, 2.) THF, 25 deg C, 24 h

2: 81 percent / diisopropylethylamine / dimethylformamide / 2 h / 25 °C

3: 96 percent / ethyl chloroformate / tetrahydrofuran / 3 h / 0 °C

4: 1.) Mg, 2.) 0.5percent H₂SO₄ / 1.) THF, 25 deg C, 12 h, 2.) MeOH, ether, 25 deg C, 2 h

5: 93 percent / NaI, trimethylsilyl chloride / acetonitrile / 0.5 h / 25 °C

6: 68 percent / AgClO₄ / acetonitrile / 24 h / 25 °C

7: 33 percent / methanol / 24 h / Irradiation

With n-butyllithium; chloro-trimethyl-silane; sulfuric acid; silver perchlorate; chloroformic acid ethyl ester; magnesium; N-ethyl-N,N-diisopropylamine; sodium iodide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; acetonitrile;