methyl 2-(4-methoxyphenoxy)acetate

Base Information

• Chemical Name: methyl 2-(4-methoxyphenoxy)acetate
• CAS No.: 79704-02-2
• Molecular Formula: C10H12 O4
• Molecular Weight: 196.203
• Mol file: 79704-02-2.mol

Synonyms:Aceticacid, (4-methoxyphenoxy)-, methyl ester (9CI); Acetic acid,(p-methoxyphenoxy)-, methyl ester (7CI); (4-Methoxyphenoxy)acetic acid methylester; Methyl (4-methoxyphenoxy)acetate; Methyl p-methoxyphenoxyacetate

Chemical Property of methyl 2-(4-methoxyphenoxy)acetate

Chemical Property:

• Vapor Pressure: 0.00353mmHg at 25°C
• Melting Point: 50 °C
• Boiling Point: 281.6°C at 760 mmHg
• Flash Point: 120.8°C
• PSA: 44.76000
• Density: 1.128g/cm³
• LogP: 1.24700

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Methyl2-(4-methoxyphenoxy)acetate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-(4-methoxyphenoxy)acetate

There total 5 articles about methyl 2-(4-methoxyphenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(4-methoxyphenoxy)acetic acid (1877-75-4) + methyl 1-imidazolecarboxylate (61985-23-7) → (4-methoxyphenoxy)acetic acid methyl ester (79704-02-2)

Guidance literature:

In acetonitrile; at 80 ℃; for 24h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ol1018882

Reference yield: 94.0%

methanol (67-56-1) + 2-(4-methoxyphenoxy)acetic acid (1877-75-4) → (4-methoxyphenoxy)acetic acid methyl ester (79704-02-2)

Guidance literature:

With toluene-4-sulfonic acid; at 20 ℃;

DOI:10.1007/s00044-009-9170-3

Reference yield:

methyl chloroacetate (96-34-4) + 4-methoxy-phenol (150-76-5) → (4-methoxyphenoxy)acetic acid methyl ester (79704-02-2)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone;

upstream raw materials:

methanol

2-(4-methoxyphenoxy)acetic acid

diazomethane

methyl chloroacetate

Downstream raw materials:

2-(4-methoxyphenoxy)acetic acid

2-(4-methoxy-phenoxy)-thioacetamide

benzyl (4-methoxyphenoxy)acetate

5-methoxy-benzofuran-2-carboxylic acid methyl ester