neurokinin A(4-10)

Base Information

• Chemical Name: neurokinin A(4-10)
• CAS No.: 97559-35-8
• Molecular Formula: C₃₄H₅₄N₈O₁₀S
• Molecular Weight: 766.916
• DSSTox Substance ID: DTXSID50913838
• Nikkaji Number: J292.934A
• Wikidata: Q82884535
• ChEMBL ID: CHEMBL126294
• Mol file: 97559-35-8.mol

Synonyms:neurokinin A(4-10);NKA-(4-10)

Chemical Property of neurokinin A(4-10)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.565
• Boiling Point: 1231.2 °C at 760 mmHg
• PKA: 3.69±0.10(Predicted)
• Flash Point: 698.4 °C
• PSA: 326.54000
• Density: 1.276 g/cm³
• LogP: 1.25010
• Storage Temp.: −20°C
• XLogP3: -3
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 24
• Exact Mass: 766.36836112
• Heavy Atom Count: 53
• Complexity: 1260

Purity/Quality:

98%Min ^*data from raw suppliers

NEUROKININ A (4 - 10) 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CO)NC(=O)C(CC(=O)O)N
• Isomeric SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)N

Technology Process of neurokinin A(4-10)

There total 1 articles about neurokinin A(4-10) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

BOC-glycine (4530-20-5) + t-Boc-L-valine (13734-41-3) + N-tert-butoxycarbonyl-L-leucine (13139-15-6,53296-34-7) + N-tert-butoxycarbonyl-L-methionine (2488-15-5) → Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 (97559-35-8)

Guidance literature:

Multistep reaction;

DOI:10.1021/jm00099a024

upstream raw materials:

BOC-glycine

t-Boc-L-valine

N-tert-butoxycarbonyl-L-leucine

N-tert-butoxycarbonyl-L-methionine