4-ETHOXYBENZHYDRAZIDE

Base Information

• Chemical Name: 4-ETHOXYBENZHYDRAZIDE
• CAS No.: 58586-81-5
• Molecular Formula: C9H12 N2 O2
• Molecular Weight: 180.206
• Hs Code.: 2928000090
• Mol file: 58586-81-5.mol

Synonyms:Benzoicacid, p-ethoxy-, hydrazide (6CI); 4-Ethoxybenzenecarbohydrazide;4-Ethoxybenzohydrazide; 4-Ethoxybenzoic acid hydrazide;4-Ethoxybenzoylhydrazine

Chemical Property of 4-ETHOXYBENZHYDRAZIDE

Chemical Property:

• Melting Point: 126-128°C
• Boiling Point: °Cat760mmHg
• PKA: 12.67±0.10(Predicted)
• Flash Point: °C
• PSA: 64.35000
• Density: 1.144g/cm³
• LogP: 1.78000

Purity/Quality:

99% ^*data from raw suppliers

4-Ethoxybenzhydrazide ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ETHOXYBENZHYDRAZIDE

There total 6 articles about 4-ETHOXYBENZHYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.4%

methyl 4-ethoxybenzoate (23676-08-6) → 4-ethoxybenzohydrazide (58586-81-5)

Guidance literature:

With hydrazine hydrate; In methanol; for 0.0833333h; Microwave irradiation;

Reference yield:

ethyl 4-ethoxybenzoate (23676-09-7) → 4-ethoxybenzohydrazide (58586-81-5)

Guidance literature:

With hydrazine hydrate;

Reference yield:

4-(ethoxy)benzoic acid (619-86-3) → 4-ethoxybenzohydrazide (58586-81-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄ / Heating

2: hydrazine / ethanol; H₂O / 3 h / Heating

With sulfuric acid; hydrazine; In ethanol; water;

DOI:10.1021/jo049088f

upstream raw materials:

ethyl 4-ethoxybenzoate

methyl 4-ethoxybenzoate

4-(ethoxy)benzoic acid

Ethyl 4-hydroxybenzoate

Downstream raw materials:

4-ethoxy benzoyl azide

2-(4-Ethoxyphenyl)-5-((2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)thio)-1,3,4-oxadiazole

{3,5-(dimethylpyrazol-1-yl)-4-ethoxy-1-carbonyl}benzene

N'-(2-methoxybenzylidene)-4-ethoxybenzohydrazide