(Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione

Base Information

• Chemical Name: (Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione
• CAS No.: 24044-50-6
• Molecular Formula: C11H9 N O4 S
• Molecular Weight: 251.263
• NSC Number: 31206
• ChEMBL ID: CHEMBL232380

Synonyms:(Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione;CHEMBL232380;911714-34-6;24044-50-6;(5Z)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione;NSC31206;SCHEMBL1248757;BDBM50213304;NSC-31206;AKOS000270993;5-(4-hydroxy-3-methoxybenzylidene)-2,4-thiazolidinedione;5-(4-hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione

Chemical Property of (Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.5g/cm³
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 251.02522894
• Heavy Atom Count: 17
• Complexity: 369

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=CC(=C1)C=C2C(=O)NC(=O)S2)O
• Isomeric SMILES: COC1=C(C=CC(=C1)/C=C\2/C(=O)NC(=O)S2)O

Technology Process of (Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione

There total 1 articles about (Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

thiazoline-2,4-dione (2295-31-0) + vanillin (121-33-5,8014-42-4) → 5-(4-hydroxy-3-methoxybenzylidene)-1,3-thiazolidine-2,4-dione (24044-50-6)

Guidance literature:

With piperidine; acetic acid; In toluene; at 80 ℃; Dean-Stark;

Reference yield: 83.8%

5-(4-hydroxy-3-methoxybenzylidene)-1,3-thiazolidine-2,4-dione (24044-50-6) + 2-Chloro-N,N-diethylacetamide (2315-36-8) → 2-(5-(4-hydroxy-3-methoxybenzylidene)-2,4-dioxothiazolidin-3-yl)-N,N-diethylacetamide

Guidance literature:

With triethylamine; In acetonitrile; Reflux;

DOI:10.1016/j.ejmech.2021.113630

Reference yield: 70.56%

4-(chloroacetyl)biphenyl (635-84-7) + 5-(4-hydroxy-3-methoxybenzylidene)-1,3-thiazolidine-2,4-dione (24044-50-6) → 3-(2-biphenyl-4-yl-2-oxo-ethyl)-5-(4-hydroxy-3-methoxy-benzylidene)-thiazolidine-2,4-dione (1235470-91-3)

Guidance literature:

With potassium carbonate; In acetonitrile; Reflux;

upstream raw materials:

thiazoline-2,4-dione

vanillin

Downstream raw materials:

3-(2-biphenyl-4-yl-2-oxo-ethyl)-5-(4-hydroxy-3-methoxy-benzylidene)-thiazolidine-2,4-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 24044-50-6 5-(4-hydroxy-3-methoxybenzylidene)-1,3-thiazolidine-2,4-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send