Gyno-Pevaril

Base Information

Chemical Name:Gyno-Pevaril
CAS No.:68797-30-8
Molecular Formula:C₁₈H₁₅Cl₃N₂O
Molecular Weight:381.689
Hs Code.:
European Community (EC) Number:272-294-0
DSSTox Substance ID:DTXSID50988506

Synonyms:Econazole;Econazole Nitrate;Ekonazole;Gyno Pervaryl 150;Gyno Pevaril;Gyno Pevaryl;Gyno-Pervaryl 150;Gyno-Pevaril;Gyno-Pevaryl;GynoPevaril;Nitrate, Econazole;Pevaryl

Suppliers and Price of Gyno-Pevaril

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Gyno-Pevaril

Chemical Property:

Vapor Pressure:5.15E-09mmHg at 25°C
Boiling Point:482.9°Cat760mmHg
Flash Point:245.9°C
Density:1.36g/cm³
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:380.024996
Heavy Atom Count:24
Complexity:452

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1COC(CC2C=NC=N2)C3=C(C=C(C=C3)Cl)Cl)Cl

Technology Process of Gyno-Pevaril

There total 7 articles about Gyno-Pevaril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.4%

: 24155-42-8
1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol

: 27220-47-9,68797-30-8,73094-37-8,73094-39-0
econazole

Guidance literature:: 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol; With sodium hydride; In N,N-dimethyl-formamide; at -5 - 20 ℃; for 1.5h; Inert atmosphere;

4-chlorobenzyl halide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.bmc.2018.02.014

Reference yield:

: 46503-52-0
1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanone

: 27220-47-9,68797-30-8,73094-37-8,73094-39-0
econazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 20 °C

2: potassium iodide / acetonitrile / Reflux

With sodium tetrahydroborate; potassium iodide; In methanol; acetonitrile;
DOI:10.1039/C6SC05368H

Reference yield:

: 4252-78-2
2,2',4'-trichloroacetophenone

: 27220-47-9,68797-30-8,73094-37-8,73094-39-0
econazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetonitrile

2: sodium tetrahydroborate / methanol / 20 °C

3: potassium iodide / acetonitrile / Reflux

With sodium tetrahydroborate; potassium carbonate; potassium iodide; In methanol; acetonitrile;
DOI:10.1039/C6SC05368H