4-{(e)-[(3-Chlorophenyl)imino]methyl}-n,n-dimethylaniline

Base Information

• Chemical Name: 4-{(e)-[(3-Chlorophenyl)imino]methyl}-n,n-dimethylaniline
• CAS No.: 92573-45-0
• Molecular Formula: C15H15ClN2
• Molecular Weight: 258.746
• European Community (EC) Number: 653-057-4
• NSC Number: 158580
• DSSTox Substance ID: DTXSID10303498
• Nikkaji Number: J387.774D
• Mol file: 92573-45-0.mol

Synonyms:92573-45-0;NSC158580;4-{(e)-[(3-chlorophenyl)imino]methyl}-n,n-dimethylaniline;DTXSID10303498;AKOS024333411;NSC-158580;ALPHA-(3-CHLOROPHENYLIMINO)-N,N-DIMETHYL-P-TOLUIDINE

Chemical Property of 4-{(e)-[(3-Chlorophenyl)imino]methyl}-n,n-dimethylaniline

Chemical Property:

• Vapor Pressure: 8.18E-07mmHg at 25°C
• Boiling Point: 406.4°Cat760mmHg
• Flash Point: 199.6°C
• Density: 1.07g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 258.0923762
• Heavy Atom Count: 18
• Complexity: 270

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C=NC2=CC(=CC=C2)Cl

Technology Process of 4-{(e)-[(3-Chlorophenyl)imino]methyl}-n,n-dimethylaniline

There total 1 articles about 4-{(e)-[(3-Chlorophenyl)imino]methyl}-n,n-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-chloro-aniline (108-42-9) + 4-dimethylamino-benzaldehyde (100-10-7) → 4-((3-chlorophenylimino)methyl)-N,N-dimethylaniline (92573-45-0)

Guidance literature:

In neat(no solvent); at 110 ℃; for 0.0166667h; Microwave irradiation;

DOI:10.1002/jhet.604

Reference yield: 64.0%

4-((3-chlorophenylimino)methyl)-N,N-dimethylaniline (92573-45-0) + phenylacetyl chloride (103-80-0) → 1-(3-chlorophenyl)-4-(4-(dimethylamino)phenyl)-3-phenylazetidin-2-one

Guidance literature:

With triethylamine; In dichloromethane; for 14h;

DOI:10.1002/jhet.604

Reference yield: 41.0%

chloranil (118-75-2) + 4-((3-chlorophenylimino)methyl)-N,N-dimethylaniline (92573-45-0) → 2,5-dichloro-3,6-bis-(3-chloro-anilino)-[1,4]benzoquinone (136113-26-3)

Guidance literature:

With oxygen; In ethyl acetate; for 48h; Ambient temperature;

DOI:10.1246/bcsj.64.1966

upstream raw materials:

3-chloro-aniline

4-dimethylamino-benzaldehyde

Downstream raw materials:

2,5-dichloro-3,6-bis-(3-chloro-anilino)-[1,4]benzoquinone