1-Bromo-2-chloro-1,1,2-trifluoroethane

Base Information

• Chemical Name: 1-Bromo-2-chloro-1,1,2-trifluoroethane
• CAS No.: 354-06-3
• Molecular Formula: C2H Br Cl F3
• Molecular Weight: 197.382
• Hs Code.: 2903799090
• European Community (EC) Number: 206-544-7
• NSC Number: 123315
• UNII: 11Q6C1GL2E
• DSSTox Substance ID: DTXSID70861887
• Nikkaji Number: J42.988K
• Wikidata: Q27251333
• Mol file: 354-06-3.mol

Synonyms:1,1,2-trifluoro-1-bromo-2-chloroethane

Chemical Property of 1-Bromo-2-chloro-1,1,2-trifluoroethane

Chemical Property:

• Vapor Pressure: 263mmHg at 25°C
• Refractive Index: 1.3721 (estimate)
• Boiling Point: 54 °C at 760 mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: 1.918 g/cm³
• LogP: 2.50850
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 195.89022
• Heavy Atom Count: 7
• Complexity: 66

Purity/Quality:

98%min ^*data from raw suppliers

1-Bromo-2-chloro-1,1,2-trifluoroethane 99% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 41-59
• Safety Statements: 26-36/37/39-45

MSDS Files:

Useful:

• Canonical SMILES: C(C(F)(F)Br)(F)Cl

Technology Process of 1-Bromo-2-chloro-1,1,2-trifluoroethane

There total 8 articles about 1-Bromo-2-chloro-1,1,2-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1,2-dibromo-1-chloro-1,2,2-trifluoroethane (354-51-8) → 1-bromo-2-chloro-1,1,2-trifluoroethane (354-06-3)

Guidance literature:

With sodium hypophosphite; sodium acetate; platinum on activated charcoal; In acetic acid; at 40 ℃; for 6h;

DOI:10.1016/S0022-1139(00)81258-0

Reference yield:

Chlorotrifluoroethylene (79-38-9,9036-80-0) → 1-bromo-2-chloro-1,1,2-trifluoroethane (354-06-3)

Guidance literature:

With hydrogen bromide; im UV-Licht;

DOI:10.1039/jr9540003747

Reference yield:

Chlorotrifluoroethylene (79-38-9,9036-80-0) + hydrogen bromide (10035-10-6,12258-64-9) → 1-bromo-2-chloro-1,1,2-trifluoroethane (354-06-3)

Guidance literature:

at 90 ℃;

DOI:10.1021/ja01175a023

upstream raw materials:

Chlorotrifluoroethylene

1,2-dibromo-1-chloro-1,2,2-trifluoroethane

hydrogen bromide

ethanol

Downstream raw materials:

1,1,2-trifluoroethylene

Refernces