3-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)propan-1-one;hydrochloride

Base Information

• Chemical Name: 3-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)propan-1-one;hydrochloride
• CAS No.: 6309-85-9
• Molecular Formula: C12H17NO3
• Molecular Weight: 223.2683
• DSSTox Substance ID: DTXSID30589575
• NSC Number: 41641
• Mol file: 6309-85-9.mol

Synonyms:6309-85-9;DTXSID30589575;NSC41641;NSC-41641;3-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)propan-1-one--hydrogen chloride (1/1)

Chemical Property of 3-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)propan-1-one;hydrochloride

Chemical Property:

• Vapor Pressure: 5.08E-06mmHg at 25°C
• Boiling Point: 370.7°Cat760mmHg
• Flash Point: 178°C
• Density: 1.115g/cm³
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 259.0975211
• Heavy Atom Count: 17
• Complexity: 230

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC(=O)C1=CC(=C(C=C1)O)OC.Cl

Technology Process of 3-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)propan-1-one;hydrochloride

There total 1 articles about 3-(Dimethylamino)-1-(4-hydroxy-3-methoxyphenyl)propan-1-one;hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N,N-dimethylammonium chloride (506-59-2) + 1-(3-methoxy-4-hydroxyphenyl)ethanone (498-02-2) → 1-hydroxy-4-(3-dimethylaminopropionyl)-2-methoxybenzene hydrochloride (6309-85-9)

Guidance literature:

With hydrogenchloride; In isopropyl alcohol; for 5h; Heating;

DOI:10.1007/BF02219312

Reference yield:

1-hydroxy-4-(3-dimethylaminopropionyl)-2-methoxybenzene hydrochloride (6309-85-9) → 3-dimethylamino-1-(4-hydroxy-3-methoxy-phenyl)-propan-1-ol; hydrochloride (104743-63-7)

Guidance literature:

With acetic acid; platinum; Hydrogenation;

upstream raw materials:

formaldehyd

N,N-dimethylammonium chloride

1-(3-methoxy-4-hydroxyphenyl)ethanone

Downstream raw materials:

3-dimethylamino-1-(4-hydroxy-3-methoxy-phenyl)-propan-1-ol; hydrochloride