1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride

Base Information

Chemical Name:1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride
CAS No.:117052-22-9
Molecular Formula:C₁₃H₁₈BrNO₃*ClH
Molecular Weight:352.656
Hs Code.:
DSSTox Substance ID:DTXSID50151697

Synonyms:5-Bromo-1-(3-dimethylaminopropionyl)-2,3-dimethoxybenzene hydrochloride;1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride;1-(5-Bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-1-propanone hydrochloride;117052-22-9;C13H18BrNO3.ClH;DTXSID50151697;LS-122775

Suppliers and Price of 1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride

Chemical Property:

Vapor Pressure:6.54E-06mmHg at 25°C
Boiling Point:377.9°Cat760mmHg
Flash Point:182.3°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:351.02368
Heavy Atom Count:19
Complexity:273

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCC(=O)C1=C(C(=CC(=C1)Br)OC)OC.Cl

Technology Process of 1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride

There total 3 articles about 1-Propanone, 1-(5-bromo-2,3-dimethoxyphenyl)-3-(dimethylamino)-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 7507-91-7
1-(5-bromo-2,3-dimethoxy-phenyl)-ethanone

: 506-59-2
N,N-dimethylammonium chloride

: 117052-22-9
1-(5-Bromo-2,3-dimethoxy-phenyl)-3-dimethylamino-propan-1-one; hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 10h; Heating;
DOI:10.1007/BF00763527

Reference yield:

: 71295-21-1
5-bromo-2,3-dimethoxybenzaldehyde

: 117052-22-9
1-(5-Bromo-2,3-dimethoxy-phenyl)-3-dimethylamino-propan-1-one; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Mg / 2.) ether, benzene, reflux, 6 h

2: 86 percent / CrO₃, pyridine / CH₂Cl₂ / 0.25 h

3: 70 percent / aq. conc. HCl / ethanol / 10 h / Heating

With pyridine; chromium(VI) oxide; hydrogenchloride; magnesium; In ethanol; dichloromethane;
DOI:10.1007/BF00763527

Reference yield:

: 117052-17-2
1-(5-Bromo-2,3-dimethoxy-phenyl)-ethanol

: 117052-22-9
1-(5-Bromo-2,3-dimethoxy-phenyl)-3-dimethylamino-propan-1-one; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / CrO₃, pyridine / CH₂Cl₂ / 0.25 h

2: 70 percent / aq. conc. HCl / ethanol / 10 h / Heating

With pyridine; chromium(VI) oxide; hydrogenchloride; In ethanol; dichloromethane;
DOI:10.1007/BF00763527