3-PHENYL-3-PENTANOL

Base Information

• Chemical Name: 3-PHENYL-3-PENTANOL
• CAS No.: 1565-71-5
• Molecular Formula: C11H16 O
• Molecular Weight: 164.247
• Hs Code.: 2906299090
• Mol file: 1565-71-5.mol

Synonyms:Benzylalcohol, a,a-diethyl- (6CI,7CI,8CI); 3-Pentanol, 3-phenyl-;3-Phenyl-3-pentanol; Diethylphenylcarbinol; NSC 401895; NSC 42888; a,a-Diethylbenzyl alcohol

Chemical Property of 3-PHENYL-3-PENTANOL

Chemical Property:

• Vapor Pressure: 0.0573mmHg at 25°C
• Refractive Index: 1.5160
• Boiling Point: 257.9°Cat760mmHg
• PKA: 14.49±0.29(Predicted)
• Flash Point: 107.1°C
• PSA: 20.23000
• Density: 0.965g/cm³
• LogP: 2.69420

Purity/Quality:

99% ^*data from raw suppliers

3-Phenylpentan-3-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It finds its application in the synthesis and physical properties of some c12 and c13 phenylalkane and cyclohexylalkane hydrocarbons and in the dehydration of Alcohols in Dimethyl Sulfoxide1,2.

Technology Process of 3-PHENYL-3-PENTANOL

There total 65 articles about 3-PHENYL-3-PENTANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

ethylmagnesium bromide (925-90-6) + methyllithium (917-54-4) + 1-phenyl-propan-1-one (93-55-0) → 2-phenyl-2-butanol (1565-75-9,19641-57-7) + 3-phenylpentan-3-ol (1565-71-5)

Guidance literature:

ethylmagnesium bromide; methyllithium; In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;

1-phenyl-propan-1-one; In tetrahydrofuran; diethyl ether; at -78 ℃; for 5h;

DOI:10.1021/ol047685i

Reference yield: 89.0%

phenylmagnesium bromide + pentan-3-one (96-22-0) → 3-phenylpentan-3-ol (1565-71-5)

Guidance literature:

for 3h; Heating;

Reference yield: 83.0%

phenylmagnesium bromide (100-58-3) + pentan-3-one (96-22-0) → 3-phenylpentan-3-ol (1565-71-5)

Guidance literature:

In diethyl ether; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01691

upstream raw materials:

benzoic acid methyl ester

ethylmagnesium iodide

benzoyl cyanide

ethylmagnesium bromide

Downstream raw materials:

1-ethyl-1-phenylpropyl hydroperoxide

α-Ethyl-α-phenylbutyric acid

(1-ethyl-1-chloropropyl)benzene

3-phenylpent-2-ene

Refernces

• 1、 Chen, Dake,Berhane, Ilyas A.,Chemler, Sherry R.. "Copper-Catalyzed Enantioselective Hydroalkoxylation of Alkenols for the Synthesis of Cyclic Ethers". supporting information. p. 7409 - 7414. Retrieved 2020/06/29.
• 2、 Oyama, Ryoko,Abe, Manabu. "Reactivity and Product Analysis of a Pair of Cumyloxyl and tert-Butoxyl Radicals Generated in Photolysis of tert-Butyl Cumyl Peroxide". . p. 8627 - 8638. Retrieved 2020/07/21.