2,3-Pyrazinedicarboxylic acid

Base Information

• Chemical Name: 2,3-Pyrazinedicarboxylic acid
• CAS No.: 89-01-0
• Molecular Formula: C6H4N2O4
• Molecular Weight: 168.109
• Hs Code.: 29339900
• European Community (EC) Number: 201-875-3
• NSC Number: 1908
• UNII: QNN35WOF29
• DSSTox Substance ID: DTXSID70237467
• Nikkaji Number: J60.120I
• Wikidata: Q27287370
• ChEMBL ID: CHEMBL2000672
• Mol file: 89-01-0.mol

Synonyms:2,3-pyrazinedicarboxylic acid

Chemical Property of 2,3-Pyrazinedicarboxylic acid

Chemical Property:

• Appearance/Colour: white to pale brown crystalline powder
• Vapor Pressure: 7.51E-09mmHg at 25°C
• Melting Point: 185-188 °C
• Refractive Index: 1.4738 (estimate)
• Boiling Point: 449.1 °C at 760 mmHg
• PKA: 1.66±0.10(Predicted)
• Flash Point: 225.4 °C
• PSA: 100.38000
• Density: 1.665 g/cm³
• LogP: -0.12700
• Storage Temp.: Store below +30°C.
• Solubility.: soluble
• Water Solubility.: soluble
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 168.01710661
• Heavy Atom Count: 12
• Complexity: 184

Purity/Quality:

98%, ^*data from raw suppliers

2,3-Pyrazinedicarboxylic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C
• Hazard Codes: F,C
• Statements: 36/37/38-34-11
• Safety Statements: 22-24/25-45-36/37/39-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CN=C(C(=N1)C(=O)O)C(=O)O
• Uses: 2,3-Pyrazinedicarboxylic Acid has been found to exhibit antifungal and antibacterial acitivity. It has also been used as a reagent in the preparation of transition metal pyrazinedicarboxylate complexes.

Technology Process of 2,3-Pyrazinedicarboxylic acid

There total 13 articles about 2,3-Pyrazinedicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

pyrazine-2,3-dicarboxylatocopper(II) (46150-15-6) → 2,3-dicarboxypyrazine (89-01-0)

Guidance literature:

With water; sodium hydroxide; at 90 ℃; for 2h;

Reference yield: 71.0%

2,3-diethynylquinoxaline (91-19-0) → 2,3-dicarboxypyrazine (89-01-0)

Guidance literature:

With potassium permanganate; In water; at 95 ℃;

DOI:10.1002/hlca.19940770610

Reference yield: 70.0%

2,3-Diaminosuccinic acid (921-52-8) + Glyoxal (131543-46-9,107-22-2) → 2,3-dicarboxypyrazine (89-01-0)

Guidance literature:

With sodium hydroxide; In methanol; 1) 50 deg C, 30 min, 2) relux, 3h;

upstream raw materials:

2,3-diethynylquinoxaline

pyrazine-2,3-dicarbonitrile

2,3-Diaminosuccinic acid

Glyoxal

Downstream raw materials:

pyrazine-2,3-dicarboxylic acid dimethyl ester

2,3-pyrazinedicarboxylic anhydride

pyrazine-2,3-dicarboxylic acid diphenacyl ester

pyrazinamide