2,3-Dichlorobenzyl alcohol

Base Information

• Chemical Name: 2,3-Dichlorobenzyl alcohol
• CAS No.: 38594-42-2
• Molecular Formula: C7H6Cl2O
• Molecular Weight: 177.03
• Hs Code.: 29062990
• European Community (EC) Number: 625-840-0
• DSSTox Substance ID: DTXSID10281429
• Nikkaji Number: J89.237H
• Wikidata: Q82015364
• Mol file: 38594-42-2.mol

Synonyms:2,3-Dichlorobenzyl alcohol;(2,3-dichlorophenyl)methanol;38594-42-2;MFCD00238581;(2,3-dichlorophenyl)methan-1-ol;SCHEMBL111152;(2,3-dichloro-phenyl)-methanol;STVBVTWXWZMRPZ-UHFFFAOYSA-;DTXSID10281429;2,3-Dichlorobenzyl alcohol, 97%;AKOS000249314;NCGC00166214-01;AC-26184;AS-10305;SY052701;CS-0157236;D2425;FT-0653337;A22380;EN300-182218;Dichlorobenzylalcohol;(2,3-Dichlorophenyl)methanol;InChI=1/C7H6Cl2O/c8-6-3-1-2-5(4-10)7(6)9/h1-3,10H,4H2;6B0

Chemical Property of 2,3-Dichlorobenzyl alcohol

Chemical Property:

• Appearance/Colour: white crystalline powder
• Melting Point: 85-88 °C(lit.)
• Boiling Point: 271.2 °C at 760 mmHg
• PKA: 13.69±0.10(Predicted)
• Flash Point: 115.8 °C
• PSA: 20.23000
• Density: 1.392 g/cm³
• LogP: 2.48570
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 175.9795702
• Heavy Atom Count: 10
• Complexity: 108

Purity/Quality:

97% ^*data from raw suppliers

(2,3-Dichlorophenyl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)Cl)CO
• Uses: 2,3-Dichlorobenzyl alcohol may be used in the preparation of methyl [2,3-dichlorobenzyl 4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-5-(2-nitrophenylsulfonamido)-D-glycero-α-D-galacto-2-nonulopyranosid]onate and methyl [2,3-dichlorobenzyl 5-acetamido-4,7,8-tri-O-acetyl-3,5,9-trideoxy-9-(4-phenylbenzamido)-D-glycero-α-D-galacto-2-nonulopyranosid]onate.

Technology Process of 2,3-Dichlorobenzyl alcohol

There total 11 articles about 2,3-Dichlorobenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-dichlorobenzylaldehyde (6334-18-5) → 2,3-dichlorobenzyl alcohol (38594-42-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2015.12.028

Reference yield: 97.0%

→ 2,3-dichlorobenzyl alcohol (38594-42-2)

Guidance literature:

Reference yield: 95.0%

2,3-Dichlorobenzoic acid methyl ester (2905-54-6) → 2,3-dichlorobenzyl alcohol (38594-42-2)

Guidance literature:

With methanol; sodium tetrahydroborate; In tetrahydrofuran; at 65 ℃; for 2.5h;

DOI:10.1016/j.tetlet.2004.06.034

upstream raw materials:

2,3-dichlorobenzylaldehyde

2,3-Dichlorobenzoic acid methyl ester

2,3-dichloroaniline

2,3-dichlorbenzoic acid

Downstream raw materials:

2,3-dichlorobenzylaldehyde

ethyl 2-cyano-3-(2,3-dichlorophenyl)propanoate

3-(2,3-dichlorobenzyl)-5-(pyridin-4-yl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-ol

1-(bromomethyl)-2,3-dichlorobenzene