2,3-Dichlorobenzaldehyde

Base Information

• Chemical Name: 2,3-Dichlorobenzaldehyde
• CAS No.: 6334-18-5
• Molecular Formula: C7H4Cl2O
• Molecular Weight: 175.014
• Hs Code.: 29130000
• European Community (EC) Number: 228-711-3,250-492-8
• NSC Number: 28450
• UNII: H6GN7Q4PCS
• DSSTox Substance ID: DTXSID7064239
• Nikkaji Number: J81.194G
• Wikidata: Q72465441
• ChEMBL ID: CHEMBL4645306
• Mol file: 6334-18-5.mol

Synonyms:2,3-Dichlorobenzaldehyde;6334-18-5;DICHLOROBENZALDEHYDE;Benzaldehyde, dichloro-;Benzaldehyde, 2,3-dichloro-;31155-09-6;NSC 28450;H6GN7Q4PCS;CCRIS 8612;EINECS 228-711-3;EINECS 250-492-8;NSC-28450;MFCD00010127;dichlorbenzaldehyd;2,3-dichlorobenzaldehyd;Benzaldehyde,3-dichloro-;UNII-H6GN7Q4PCS;2,3-dichloro-benzaldehyde;SCHEMBL95211;2,3-bis(chloranyl)benzaldehyde;CHEMBL4645306;DTXSID7064239;2,3-Dichlorobenzaldehyde, 99%;LLMLNAVBOAMOEE-UHFFFAOYSA-;NSC28450;STK317882;AKOS000119755;2,3-Dichlorobenzaldehyde, >=98.0%;AC-3207;AM62280;CS-W018532;PS-3369;D1666;FT-0609550;FT-0651581;EN300-19650;A834336;A929310;AK-968/41169414;W-104916;F0001-1720;Z104474602

Chemical Property of 2,3-Dichlorobenzaldehyde

Chemical Property:

• Appearance/Colour: white crystalline powder
• Melting Point: 64-67 °C(lit.)
• Refractive Index: 1.5756 (estimate)
• Boiling Point: 242.9 °C at 760 mmHg
• Flash Point: 99.2 °C
• PSA: 17.07000
• Density: 1.4 g/cm³
• LogP: 2.80590
• Storage Temp.: Store below +30°C.
• Sensitive.: Air Sensitive
• Water Solubility.: Practically insoluble in water
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 173.9639201
• Heavy Atom Count: 10
• Complexity: 127

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dichlorobenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, C
• Hazard Codes: C,Xi
• Statements: 34-36/37/38
• Safety Statements: 26-36/37/39-45-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)Cl)C=O
• Uses: 2,3-Dichlorobenzaldehyde has been used in preparation of:4-(2,3-dichlorobenzylideneamino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one, Schiff baseethyl 4-(2,3-dichlorophenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate via Biginelli condensationbenzyl 4-(2,3-dichlorophenyl)-1,3,6-trimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Technology Process of 2,3-Dichlorobenzaldehyde

There total 19 articles about 2,3-Dichlorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N'-(2,3-dichloro-benzylidene)-N,N-dimethyl-hydrazine → 2,3-dichlorobenzylaldehyde (6334-18-5)

Guidance literature:

With silica gel; iron(III) chloride; for 0.01h; microwave irradiation;

Reference yield: 85.0%

2,3-dichlorobenzaldehyde oxime (4414-54-4) → 2,3-dichlorobenzylaldehyde (6334-18-5)

Guidance literature:

With quinolinium monofluorochromate(VI); In acetonitrile; for 5h; Heating;

DOI:10.1080/00397910008087132

Reference yield: 82.6%

2,3-dichlorobenzyl alcohol (38594-42-2) → 2,3-dichlorobenzylaldehyde (6334-18-5)

Guidance literature:

With oxygen; C₅₄H₆₀N₆O₆Pd⁽²⁺⁾*2Br^(1-); potassium carbonate; In toluene; at 80 ℃; for 8h; under 3750.38 Torr; Autoclave;

DOI:10.1039/d1ra05855j

upstream raw materials:

2,3-dichlorotoluene

formaldoxime

2,3-dichloroaniline

2-acetonyl-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane

Downstream raw materials:

3-(2,3-dichlorophenyl)acrylic acid

2,3-Dichloro-α-methylbenzyl alcohol

2-(2,3-dichloro-trans-styryl)-1-methyl-pyridinium; iodide

((E)-2,3-dichloro-benzyliden)-aniline

Refernces

• 1、 Abinaya, R.,Balasubramaniam, K. K.,Baskar, B.,Divya, P.,Mani Rahulan, K.,Rahman, Abdul,Sridhar, R.,Srinath, S.. "Visible light mediated selective oxidation of alcohols and oxidative dehydrogenation of N-heterocycles using scalable and reusable La-doped NiWO4nanoparticles". . p. 5990 - 6007. Retrieved 2021/08/24.
• 2、 Saka, Ece Tugba,Dügdü, Esra,ünver, Yasemin. "Degradation of substituted phenols with different oxygen sources catalyzed by Co(II) and Cu(II) phthalocyanine complexes". . p. 1119 - 1130. Retrieved 2019/05/17.