6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride

Base Information

Chemical Name:6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride
CAS No.:137376-72-8
Molecular Formula:C17H26ClNO3
Molecular Weight:327.8462
Hs Code.:
DSSTox Substance ID:DTXSID40929781
Mol file:137376-72-8.mol

Synonyms:6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride;1(2H)-Naphthalenone, 3,4-dihydro-6,7-diethoxy-2-((dimethylamino)methyl)-, hydrochloride;137376-72-8;DTXSID40929781;LS-95042;2-[(Dimethylamino)methyl]-6,7-diethoxy-3,4-dihydronaphthalen-1(2H)-one--hydrogen chloride (1/1)

Suppliers and Price of 6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride

Chemical Property:

Vapor Pressure:2.19E-07mmHg at 25°C
Boiling Point:423.7°Cat760mmHg
Flash Point:210.1°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:327.1601214
Heavy Atom Count:22
Complexity:345

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C2C(=C1)CCC(C2=O)CN(C)C)OCC.Cl

Technology Process of 6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride

There total 4 articles about 6,7-Diethoxy-2-((dimethylamino)methyl)-3,4-dihydro-1(2H)-naphthalenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 506-59-2
N,N-dimethylammonium chloride

: 119034-81-0
6,7-diethoxy-3,4-dihydro-1(2H)-naphthalenone

: 137376-72-8
2-Dimethylaminomethyl-6,7-diethoxy-3,4-dihydro-2H-naphthalen-1-one; hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 8h; Heating;
DOI:10.1007/BF00777420

Reference yield:

: 2050-46-6
1,2-diethoxybenzene

: 137376-72-8
2-Dimethylaminomethyl-6,7-diethoxy-3,4-dihydro-2H-naphthalen-1-one; hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / AlCl₃ / CH₂Cl₂ / 3 h / 20 °C

2: 89 percent / conc. HCl, amalgamated Zn / 36 h / Heating

3: 77 percent / polyphosphoric acid / 0.33 h / 110 °C

4: 75 percent / conc. HCl / ethanol / 8 h / Heating

With hydrogenchloride; aluminium trichloride; PPA; amalgamated zinc; In ethanol; dichloromethane;
DOI:10.1007/BF00777420

Reference yield:

: 63213-42-3
4-oxo-4-(3,4-diethoxyphenyl)butyric acid

: 137376-72-8
2-Dimethylaminomethyl-6,7-diethoxy-3,4-dihydro-2H-naphthalen-1-one; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / conc. HCl, amalgamated Zn / 36 h / Heating

2: 77 percent / polyphosphoric acid / 0.33 h / 110 °C

3: 75 percent / conc. HCl / ethanol / 8 h / Heating

With hydrogenchloride; PPA; amalgamated zinc; In ethanol;
DOI:10.1007/BF00777420