4-tert-Butylphenacyl chloride

Base Information

Chemical Name:4-tert-Butylphenacyl chloride
CAS No.:21886-62-4
Molecular Formula:C12H15ClO
Molecular Weight:210.704
Hs Code.:2914700090
European Community (EC) Number:672-281-3
NSC Number:23491
DSSTox Substance ID:DTXSID30281921
Nikkaji Number:J920.385K
Wikidata:Q82016046
Mol file:21886-62-4.mol

Synonyms:21886-62-4;4-tert-Butylphenacyl chloride;2-chloro-4'-tert-butylacetophenone;1-(4-tert-butylphenyl)-2-chloroethanone;1-(4-(tert-butyl)phenyl)-2-chloroethanone;Ethanone, 2-chloro-1-[4-(1,1-dimethylethyl)phenyl]-;4-(tert-Butyl)phenacyl chloride;1-(4-tert-Butyl-phenyl)-2-chloro-ethanone;1-(4-(tert-butyl)phenyl)-2-chloroethan-1-one;Ethanone, 2-chloro-1-(4-(1,1-dimethylethyl)phenyl)-;NSC23491;1-(4-tert-butylphenyl)-2-chloroethan-1-one;SCHEMBL260256;4-tert-butyl-phenacyl chloride;DTXSID30281921;4'-tert-butyl-2-chloroacetophenone;MFCD00171621;NSC 23491;NSC-23491;AKOS000115659;PS-11419;[4-(tert-Butyl)phenyl](chloromethyl) ketone;A4683;CS-0073137;FT-0630151;EN300-01981;VU0549369-1;SR-01000325713;2-chloro-1-[4-(1,1-dimethylethyl)phenyl]ethanone;SR-01000325713-1;Ethanone,2-chloro-1-[4-(1,1-dimethylethyl)phenyl]-;Z56891292;F9995-0423

Suppliers and Price of 4-tert-Butylphenacyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
4-tert-Butylphenacylchloride 96%
100g
$ 395.00

AK Scientific
2-chloro-4'-tert-butylacetophenone
250mg
$ 77.00

Alfa Aesar
4'-tert-Butyl-2-chloroacetophenone, 97%
5g
$ 218.00

Alfa Aesar
4'-tert-Butyl-2-chloroacetophenone, 97%
1g
$ 59.10

Alichem
1-(4-(tert-Butyl)phenyl)-2-chloroethanone
5g
$ 237.65

American Custom Chemicals Corporation
4-TERT-BUTYLPHENACYL CHLORIDE 95.00%
1G
$ 648.81

American Custom Chemicals Corporation
4-TERT-BUTYLPHENACYL CHLORIDE 95.00%
2.5G
$ 852.21

American Custom Chemicals Corporation
4-TERT-BUTYLPHENACYL CHLORIDE 95.00%
5G
$ 1005.43

Atlantic Research Chemicals
1-(4-tert-Butylphenyl)-2-chloroethanone 95%
250mgs:
$ 13.43

Chemenu
1-(4-tert-Butylphenyl)-2-chloroethanone 95+%
5g
$ 229.00

Total 28 raw suppliers

Chemical Property of 4-tert-Butylphenacyl chloride

Chemical Property:

Vapor Pressure:0.00112mmHg at 25°C
Melting Point:36 °C
Refractive Index:1.534
Boiling Point:300.488 °C at 760 mmHg
Flash Point:170.453 °C
PSA：17.07000
Density:1.059 g/cm³
LogP:3.40560
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:210.0811428
Heavy Atom Count:14
Complexity:197

Purity/Quality:

99%, ^*data from raw suppliers

4-tert-Butylphenacylchloride 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)C(=O)CCl
Uses 2-Chloro-4’-tert-butylacetophenone is a useful reactant and reagent for the synthesis of organic compounds such as 3-?hydroxy-?β-?lactams and terfenadine-based analogs.

Technology Process of 4-tert-Butylphenacyl chloride

There total 6 articles about 4-tert-Butylphenacyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 253185-03-4,253185-04-5
tert-butylbenzene

: 79-04-9
chloroacetyl chloride

: 21886-62-4
2-chloro-1-[4-(1,1-dimethylethyl)phenyl]ethanone

Guidance literature:: With aluminum (III) chloride; bismuth(III) chloride; In dichloromethane; at 0 - 5 ℃;
DOI:10.1080/10426500701842019

Reference yield: 90.0%

: 1746-23-2,26009-55-2
4-tert-Butylstyrene

: 21886-62-4
2-chloro-1-[4-(1,1-dimethylethyl)phenyl]ethanone

Guidance literature:: With magnesium(II) chloride hexahydrate; oxygen; lithium perchlorate; manganese(ll) chloride; In dichloromethane; acetone; at 40 ℃; for 40h; Electrochemical reaction;
DOI:10.1039/c9cc06746a