3,3-Bis(2-methylphenyl)-2-benzofuran-1(3h)-one

Base Information

Chemical Name:3,3-Bis(2-methylphenyl)-2-benzofuran-1(3h)-one
CAS No.:75195-51-6
Molecular Formula:C22H18 O2
Molecular Weight:314.384
Hs Code.:
NSC Number:143641
DSSTox Substance ID:DTXSID70301475
Wikidata:Q82045436

Synonyms:3,3-bis(2-methylphenyl)-2-benzofuran-1(3h)-one;3,3-bis(2-methylphenyl)-2-benzofuran-1-one;75195-51-6;Di-o-tolyl-phthalid;NSC143641;SCHEMBL6916063;DTXSID70301475;RPEVFIINKQHCJH-UHFFFAOYSA-N;NSC-143641

Suppliers and Price of 3,3-Bis(2-methylphenyl)-2-benzofuran-1(3h)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3,3-Bis(2-methylphenyl)-2-benzofuran-1(3h)-one

Chemical Property:

Vapor Pressure:3.43E-09mmHg at 25°C
Boiling Point:475.1°Cat760mmHg
Flash Point:201.2°C
Density:1.184g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:314.130679813
Heavy Atom Count:24
Complexity:449

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2(C3=CC=CC=C3C(=O)O2)C4=CC=CC=C4C

Technology Process of 3,3-Bis(2-methylphenyl)-2-benzofuran-1(3h)-one

There total 7 articles about 3,3-Bis(2-methylphenyl)-2-benzofuran-1(3h)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 6922-86-7
tris(o-methylphenyl)methanol

: 75195-51-6
3,3-O-di-o-tolyl-1,3-dihydro-2-benzofuran-1-one

Guidance literature:: With nitric acid; In nitrobenzene; Reflux;
DOI:10.1021/acs.orglett.9b02683

Reference yield: 37.0%

: 932-31-0
ortho-tolylmagnesium bromide

: 85-44-9
phthalic anhydride

: 75195-51-6
3,3-O-di-o-tolyl-1,3-dihydro-2-benzofuran-1-one

: 119838-09-4
di-(o-tolyl)-o-phenylenedimethanone

: o-phenyl(o-tolyl)methanone

Guidance literature:: In benzene; for 24h; Yields of byproduct given;

Reference yield:

: 6699-93-0
(2-methylphenyl)lithium

: 75195-51-6
3,3-O-di-o-tolyl-1,3-dihydro-2-benzofuran-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether

2: nitrobenzene; aqueous nitric acid

With diethyl ether; nitric acid; nitrobenzene;
DOI:10.1039/jr9510003215