N-(4-benzamidobutyl)benzamide

Base Information

• Chemical Name: N-(4-benzamidobutyl)benzamide
• CAS No.: 31991-78-3
• Molecular Formula: C18H20 N2 O2
• Molecular Weight: 296.369
• Mol file: 31991-78-3.mol

Synonyms:Benzamide,N,N'-tetramethylenebis- (6CI,7CI,8CI); Haplamide;N,N'-Dibenzoylbutane-1,4-diamine; N,N'-Tetramethylenebis[benzamide];N,N'-Tetramethylenedibenzamide; NSC 16587

Chemical Property of N-(4-benzamidobutyl)benzamide

Chemical Property:

• Boiling Point: 596.9°Cat760mmHg
• Flash Point: 225.1°C
• PSA: 58.20000
• Density: 1.122g/cm³
• LogP: 3.40840

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-benzamidobutyl)benzamide

There total 29 articles about N-(4-benzamidobutyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzoyl chloride (98-88-4) + 1,4-diaminobutane (110-60-1) → uvariadiamide (31991-78-3)

Guidance literature:

DOI:10.1021/jo00190a028

Reference yield: 78.0%

1,4-diaminobutane (110-60-1) + benzoic acid (65-85-0,8013-63-6) → uvariadiamide (31991-78-3)

Guidance literature:

With ammonium cerium (IV) nitrate; In neat (no solvent); at 160 - 165 ℃; for 2h; Microwave irradiation; Green chemistry;

DOI:10.3390/molecules25081761

Reference yield: 74.0%

N-benzoyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamide + 1,4-diaminobutane (110-60-1) → uvariadiamide (31991-78-3) + N-(4-chlorophenyl)-4-nitrobenzenesulfonamide (16937-03-4)

Guidance literature:

With potassium carbonate; In water; at 80 ℃; for 0.25h; chemoselective reaction; Green chemistry;

DOI:10.1515/znb-2015-0076

upstream raw materials:

N-benzoyl-beta-alanine

N-(4-aminobutyl)benzamide

benzoyl chloride

1,4-diaminobutane

Downstream raw materials:

1,4-dibromo-butane

N-(4-aminobutyl)benzamide

N-(4-chlorobutyl)benzamide

1,4-diaminobutane