2-(Ethylamino)propiophenone hydrochloride

Base Information

• Chemical Name: 2-(Ethylamino)propiophenone hydrochloride
• CAS No.: 51553-17-4
• Molecular Formula: C11H15NO^.HCl
• Molecular Weight: 213.707
• Hs Code.: 2922399090
• Mol file: 51553-17-4.mol

Synonyms:1-Propanone, 2-(ethylamino)-1-phenyl-, hydrochloride (9CI);RMI 8201A;2-(Ethylamino)-1-phenyl-1-propanone hydrochloride;2-(Ethylamino)-1-phenyl-1-propanone hydrochloride (1:1);

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Chemical Property of 2-(Ethylamino)propiophenone hydrochloride

Chemical Property:

• Appearance/Colour: white solid
• Vapor Pressure: 0.00613mmHg at 25°C
• Melting Point: 195-198 °C
• Boiling Point: 272.3 °C at 760 mmHg
• Flash Point: 105 °C
• PSA: 29.10000
• LogP: 3.06020
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere

Purity/Quality:

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T,F
• Statements: 36/37/38-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-45-36/37-16-7

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Ethcathinone is a metabolite of Diethylpropion. It is a cathinone derivative that produces amphetamine-like stimulus effects

Technology Process of 2-(Ethylamino)propiophenone hydrochloride

There total 1 articles about 2-(Ethylamino)propiophenone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethylamine (75-04-7,85404-22-4) + 2-bromo-1-phenyl-1-propanone (2114-00-3) → 2-ethylamino-1-phenyl-propan-1-one; hydrochloride (51553-17-4)

Guidance literature:

ethylamine; 2-bromo-1-phenyl-1-propanone; In tetrahydrofuran;

With hydrogenchloride; In diethyl ether; water;

DOI:10.1002/rcm.6383

Reference yield: 97.0%

2-ethylamino-1-phenyl-propan-1-one; hydrochloride (51553-17-4) + bis(iodozinc)methane (31729-70-1) → ethyl-(1-methyl-2-phenyl-allyl)-amine

Guidance literature:

In tetrahydrofuran; at 25 ℃;

DOI:10.1055/s-2001-12336

Reference yield: 85.0%

4-(4-carboxy-thiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester (365413-00-9) + 2-ethylamino-1-phenyl-propan-1-one; hydrochloride (51553-17-4) → tert-butyl-4-{4-[ethyl(1-methyl-2-oxo-2-phenylethyl)carbamoyl]thiazol-2-yl}-piperidine-1-carboxylate

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃;

upstream raw materials:

ethylamine

2-bromo-1-phenyl-1-propanone

Downstream raw materials:

3-ethyl-4-methyl-5-phenyl-3H-oxazol-2-ylideneamine

α-(N-Ethyl-N-benzoylamino)-propiophenon

N-(3-ethyl-4-methyl-5-phenyl-3H-oxazol-2-ylidene)-acetamide

Propane-1-sulfonic acid ethyl-(1-methyl-2-oxo-2-phenyl-ethyl)-amide

Refernces