2-Butoxyoxane

Base Information

• Chemical Name: 2-Butoxyoxane
• CAS No.: 1927-68-0
• Molecular Formula: C9H18 O2
• Molecular Weight: 158.241
• Hs Code.: 2932999099
• NSC Number: 97537
• UNII: RU757R24GH
• DSSTox Substance ID: DTXSID40294643
• Nikkaji Number: J100.903F
• Mol file: 1927-68-0.mol

Synonyms:2-Butoxyoxane;2-Butoxytetrahydro-2H-pyran;1927-68-0;2-Butoxytetrahydropyran;2H-Pyran, 2-butoxytetrahydro-;NSC-97537;NSC97537;Pyran, 2-butoxytetrahydro-;Butyl tetrahydropyranyl ether;RU757R24GH;SCHEMBL2738489;2-Butoxytetrahydro-2H-pyran #;DTXSID40294643;HVHNQFALNKRKQY-UHFFFAOYSA-N;MFCD31807279;AKOS037645236;AS-58981;CS-0161423;D80647

Chemical Property of 2-Butoxyoxane

Chemical Property:

• Vapor Pressure: 0.589mmHg at 25°C
• Boiling Point: 195.4°Cat760mmHg
• Flash Point: 58.3°C
• PSA: 18.46000
• Density: 0.92g/cm³
• LogP: 2.32970
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 158.130679813
• Heavy Atom Count: 11
• Complexity: 93.6

Purity/Quality:

99% ^*data from raw suppliers

2-BUtoxytetrahydro-2H-pyran 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCOC1CCCCO1

Technology Process of 2-Butoxyoxane

There total 5 articles about 2-Butoxyoxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dihydro-2H-pyran (110-87-2) + butan-1-ol (71-36-3) → 2-butoxytetrahydropyran (1927-68-0)

Guidance literature:

With 2Al⁽³⁺⁾*HO^(1-)*5CH₃O₃S^(1-); In dichloromethane; at 20 ℃; for 0.75h; Reagent/catalyst;

DOI:10.1080/00958972.2017.1287907

Reference yield: 100.0%

2-butoxy-(2H)-3,4-dihydropyran (332-19-4) → 2-butoxytetrahydropyran (1927-68-0)

Guidance literature:

With hydrogen; palladium on activated carbon; at 20 ℃; for 1.5 - 4.5h; under 6000.6 Torr; Product distribution / selectivity;

Reference yield: 84.0%

2-(4-Phenylselanyl-butoxy)-tetrahydro-pyran → 2-butoxytetrahydropyran (1927-68-0)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at 67 ℃; Irradiation;

DOI:10.1016/S0040-4039(98)01347-1 DOI:10.1016/j.tet.2003.08.070

upstream raw materials:

3,4-dihydro-2H-pyran

butan-1-ol

2-butoxy-(2H)-3,4-dihydropyran

tetrahydropyran-2-yl hydroperoxide

Downstream raw materials:

2-methoxytetrahydropyran

butan-1-ol

4-bromo-1-(2-tetrahydropyranyloxy)butane

butyraldehyde

Refernces

• 1、 Kyasa, ShivaKumar,Meier, Rebecca N.,Pardini, Ruth A.,Truttmann, Tristan K.,Kuwata, Keith T.,Dussault, Patrick H.. "Synthesis of Ethers via Reaction of Carbanions and Monoperoxyacetals". . p. 12100 - 12114. Retrieved 2016/01/09.
• 2、 Zhang, Yi,Dou, Qianqian,Liu, Yuan,Dai, Liyan,Wang, Xiaozhong,Chen, Yingqi. "Tetrahydropyranylation of alcohols and phenols using polystyrene supported lewis acids as catalysts". . p. 2567 - 2572. Retrieved 2013/01/15.