1H-Pyrazolo(3,4-d)pyrimidine, 4-(methylthio)-1-beta-D-ribofuranosyl-

Base Information

Chemical Name:1H-Pyrazolo(3,4-d)pyrimidine, 4-(methylthio)-1-beta-D-ribofuranosyl-
CAS No.:60355-67-1
Molecular Formula:C₁₁H₁₄N₄O₄S
Molecular Weight:298.323
Hs Code.:
Mol file:60355-67-1.mol

Synonyms:1 beta-ribofuranosyl-4-(methylmercapto)pyrazolo(3,4-d)pyrimidine;1-RMMPP

Suppliers and Price of 1H-Pyrazolo(3,4-d)pyrimidine, 4-(methylthio)-1-beta-D-ribofuranosyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1H-Pyrazolo(3,4-d)pyrimidine, 4-(methylthio)-1-beta-D-ribofuranosyl-

Chemical Property:

Vapor Pressure:7.65E-16mmHg at 25°C
Boiling Point:612.2°C at 760 mmHg
Flash Point:324°C
PSA：138.82000
Density:1.85g/cm³
LogP:-0.84030
XLogP3:-0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:298.07357611
Heavy Atom Count:20
Complexity:352

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC=NC2=C1C=NN2C3C(C(C(O3)CO)O)O
Isomeric SMILES:CSC1=NC=NC2=C1C=NN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O

Technology Process of 1H-Pyrazolo(3,4-d)pyrimidine, 4-(methylthio)-1-beta-D-ribofuranosyl-

There total 6 articles about 1H-Pyrazolo(3,4-d)pyrimidine, 4-(methylthio)-1-beta-D-ribofuranosyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 74-93-1
methylthiol

: 78586-33-1
4-chloro-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine

: 60355-67-1
4-(methylthio)-1-β-D-ribofuranosyl-1H-pyrazolo<3,4-d>pyrimidine

Guidance literature:: With sodium; In ethanol; for 18h; Heating;
DOI:10.1021/jm00142a009

Reference yield:

: 5334-23-6
tisopurine

: 60355-67-1
4-(methylthio)-1-β-D-ribofuranosyl-1H-pyrazolo<3,4-d>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / H₂O / 888 h / 35 °C / purine nucleoside phosphorylase, uridine phosphorylase, K₂HPO₄, NaN₃

2: 1.) Dowex 1-X₈ (HCO₃-form) / 1.) methanol, heating, 2.) 24 deg C, 20 h

With Dowex 1-X₈ (HCO₃-form); In water;
DOI:10.1021/jm00343a007

Reference yield:

: 58-96-8
uridine

: 60355-67-1
4-(methylthio)-1-β-D-ribofuranosyl-1H-pyrazolo<3,4-d>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / H₂O / 888 h / 35 °C / purine nucleoside phosphorylase, uridine phosphorylase, K₂HPO₄, NaN₃

2: 1.) Dowex 1-X₈ (HCO₃-form) / 1.) methanol, heating, 2.) 24 deg C, 20 h

With Dowex 1-X₈ (HCO₃-form); In water;
DOI:10.1021/jm00343a007