N-Acetyladriamycin

Base Information

Chemical Name:N-Acetyladriamycin
CAS No.:69299-74-7
Molecular Formula:C₂₉H₃₁NO₁₂
Molecular Weight:585.565
Hs Code.:
Nikkaji Number:J265.030D
ChEMBL ID:CHEMBL1956074

Synonyms:N-acetyladriamycin;N-acetyldoxorubicn;N-acetyldoxorubicn hydrochloride, (8S-cis)

Suppliers and Price of N-Acetyladriamycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-Acetyladriamycin

Chemical Property:

Vapor Pressure:1.94E-34mmHg at 25°C
Boiling Point:895.1°C at 760 mmHg
Flash Point:495.2°C
PSA：209.15000
Density:1.58g/cm³
LogP:0.56960
XLogP3:1.5
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:6
Exact Mass:585.18462542
Heavy Atom Count:42
Complexity:1080

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)C)O
Isomeric SMILES:C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)C)O

Technology Process of N-Acetyladriamycin

There total 3 articles about N-Acetyladriamycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.8%

: 23214-92-8
doxorubicin

: 64-19-7,77671-22-8
acetic acid

: 69299-74-7
N-acetyldoxorubicin

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2011.02.056

Reference yield:

: 108-24-7
acetic anhydride

: 69299-74-7
N3'-acetyl-4'-epidoxorubicin

Guidance literature:: epirubicin Hydrochloride; With N-ethyl-N,N-diisopropylamine; In acetone;

acetic anhydride; With N-ethyl-N,N-diisopropylamine; In acetone; at 0 - 20 ℃; for 2h;

Reference yield:

: 108-24-7
acetic anhydride

: 56420-45-2
epirubicin Hydrochloride

: 69299-74-7
N3'-acetyl-4'-epidoxorubicin

Guidance literature:: epirubicin Hydrochloride; With N-ethyl-N,N-diisopropylamine; In acetone;

acetic anhydride; With N-ethyl-N,N-diisopropylamine; In acetone; at 0 - 20 ℃; for 2h;