cyclohexyl[4-(dimethylamino)phenyl]methanone

Base Information

• Chemical Name: cyclohexyl[4-(dimethylamino)phenyl]methanone
• CAS No.: 4664-70-4
• Molecular Formula: C15H21NO
• Molecular Weight: 231.3333
• Mol file: 4664-70-4.mol

Synonyms:

Chemical Property of cyclohexyl[4-(dimethylamino)phenyl]methanone

Chemical Property:

• Vapor Pressure: 7.83E-06mmHg at 25°C
• Boiling Point: 375.4°Cat760mmHg
• Flash Point: 140.3°C
• Density: 1.044g/cm³

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cyclohexyl[4-(dimethylamino)phenyl]methanone

There total 9 articles about cyclohexyl[4-(dimethylamino)phenyl]methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Se-phenyl cyclohexanecarboselenoate (60718-41-4) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → cyclohexyl(4-(dimethylamino)phenyl)methanone (4664-70-4)

Guidance literature:

With 9,10-dimethoxyanthracene; In acetonitrile; at 20 ℃; Inert atmosphere; Irradiation;

DOI:10.1039/c7cc07529d

Reference yield: 76.0%

cyclohex-1-en-1-yl trifluoromethane sulfonate (28075-50-5) + 4-dimethylamino-benzaldehyde (100-10-7) → cyclohexyl(4-(dimethylamino)phenyl)methanone (4664-70-4)

Guidance literature:

With dicarbonylacetylacetonato rhodium (I); di-tert-butyl(methyl)phosphonium tetrafluoroborate salt; potassium formate; potassium carbonate; In 1,2-dimethoxyethane; at 130 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1002/chem.201903668

Reference yield: 73.0%

N-(4-(dimehtylamino)benzoyl)saccharin + 1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate (126812-30-4) → cyclohexyl(4-(dimethylamino)phenyl)methanone (4664-70-4)

Guidance literature:

With [NiBr₂(phen)]; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; lithium bromide; In N,N-dimethyl acetamide; for 24h; Inert atmosphere; Irradiation;

DOI:10.1002/chem.202103486

upstream raw materials:

N-(cyclohexanecarbonyl)piperidine

N,N-dimethyl-aniline

cyclohexyl(pyrrolidin-1-yl)methanone

Se-phenyl cyclohexanecarboselenoate

Downstream raw materials:

Cyclohexyl-<4-dimethylamino-phenyl>-keton-N-oxid

Cyclohexyl-<3-Chlor-4-dimethylamino-phenyl>-keton