1-Phenylethan-1-one hydrazone

Base Information

• Chemical Name: 1-Phenylethan-1-one hydrazone
• CAS No.: 13466-30-3
• Molecular Formula: C8H10 N2
• Molecular Weight: 134.181
• Hs Code.: 2928000090
• European Community (EC) Number: 236-717-2
• Mol file: 13466-30-3.mol

Synonyms:1-phenylethanone hydrazone;13466-30-3;(1-phenylethylidene)hydrazine;1-Phenylethan-1-one hydrazone;(E)-1-phenylethylidenehydrazine;EINECS 236-717-2;Acetophenone hydrazone;SCHEMBL1005102;SCHEMBL3655561;(E)-1-phenyl-ethylidene-hydrazine;(1E)-(1-phenylethylidene)hydrazine;AM9952;STK089395;AKOS005394119;A806818;(1-Phenylethylidene)hydrazine

Chemical Property of 1-Phenylethan-1-one hydrazone

Chemical Property:

• Vapor Pressure: 0.0335mmHg at 25°C
• Melting Point: 24-25 °C
• Boiling Point: 242.7°Cat760mmHg
• PKA: 3.13±0.70(Predicted)
• Flash Point: 100.6°C
• PSA: 38.38000
• Density: 1g/cm³
• LogP: 2.06960
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 134.084398327
• Heavy Atom Count: 10
• Complexity: 123

Purity/Quality:

99% ^*data from raw suppliers

(1-Phenylethylidene)hydrazine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NN)C1=CC=CC=C1
• Isomeric SMILES: C/C(=N\N)/C1=CC=CC=C1

Technology Process of 1-Phenylethan-1-one hydrazone

There total 20 articles about 1-Phenylethan-1-one hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetophenone (98-86-2) → (1-phenylethylidene)hydrazine (13466-30-3)

Guidance literature:

With hydrazine hydrate; In ethanol; for 6h; Heating;

Reference yield: 100.0%

acetophenone (98-86-2) → 1-(2-methylphenyl)hydrazonoethane (13466-30-3)

Guidance literature:

With hydrazine hydrate; acetic acid; In ethanol; for 4h; Reflux;

DOI:10.1080/00397911.2020.1793206

Reference yield: 99.0%

phenylacetylene (536-74-3) → (1-phenylethylidene)hydrazine (13466-30-3)

Guidance literature:

With silver hexafluoroantimonate; C₁₀H₇AuClIN₃O; hydrazine; In toluene; at 60 ℃; for 12h; Reagent/catalyst; Concentration; Temperature; Inert atmosphere;

DOI:10.1002/aoc.6098

upstream raw materials:

acetophenonazine

acetophenone

acetophenone dimethylhydrazone

acetophenonethiosemicarbazone

Downstream raw materials:

ethylbenzene

acetophenonazine

Acetanilid

C₉H₈N₂S

Refernces

• 1、 Mendoza-Espinosa, Daniel,Rendón-Nava, David,Alvarez-Hernández, Alejandro,Angeles-Beltrán, Deyanira,Negrón-Silva, Guillermo E.,Suárez-Castillo, Oscar R.. "Visible-Light-Promoted AuI to AuIII Oxidation in Triazol-5-ylidene Complexes". . p. 203 - 207. Retrieved 2017.
• 2、 Zhang, Yan,Wang, Dahai,Cui, Sunliang. "Facile Synthesis of Isoindolinones via Rh(III)-Catalyzed One-Pot Reaction of Benzamides, Ketones, and Hydrazines". . p. 2494 - 2497. Retrieved 2015.
• 3、 Ding, Wei,Dou, Qingyu,Luo, Qianfu,Wang, Lijun,Yan, Liying. "A new synthesis protocol for photochromic triarylethenes and their multifunctional derivatives". . p. 1 - 14. Retrieved 2020.
• 4、 Barluenga, Jose,Aznar, Fernando,Liz, Ramon,Bayond, Miguel. "Hydrazinomercuriation of Terminal Alkynes and 3-Alken-1-ynes. Syntheses of Hydrazones and 1-Amino-1-aza-1,3-dienes". . p. 121 - 122. Retrieved 1988.
• 5、 Mikle, Gábor,Skoda-F?ldes, Rita,Kollár, László. "Amino- and azidocarbonylation of iodoalkenes". . . Retrieved 2021/10/14.
• 6、 Liang, Qianqian,Liu, Hong-Min,Ma, Li-Ying,Ren, Hongmei,Wu, Yang,Zhang, Kun,Zhang, Xinhui,Zhao, Bing,Zheng, Yi-Chao. "Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B)". . . Retrieved 2020/03/10.