N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide

Base Information

Chemical Name:N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide
CAS No.:39719-87-4
Molecular Formula:C11H12 N4 O3 S2
Molecular Weight:312.373
Hs Code.:
European Community (EC) Number:254-606-7
DSSTox Substance ID:DTXSID30192801
Nikkaji Number:J261.437E
Wikidata:Q83065459
ChEMBL ID:CHEMBL1685032
Mol file:39719-87-4.mol

Synonyms:39719-87-4;N-(4-(N-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide;C11H12N4O3S2;N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide;EINECS 254-606-7;N-[4-[[(5-methyl-1,3,4-thiadiazol-2-yl)amino]sulphonyl]phenyl]acetamide;Oprea1_022754;Oprea1_697309;MLS001210654;SCHEMBL286629;CHEMBL1685032;DTXSID30192801;N-[4-(5-Methyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-acetamide;STK089454;AKOS000623706;N-(4-{[(5-methyl-1,3,4-thiadiazol-2-yl)amino]sulfonyl}phenyl)acetamide;C11-H12-N4-O3-S2;SMR000517633;N-{4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}acetamide;N-(5-Methyl-1,3,4-thiadiazole-2-yl)-4-(acetylamino)benzenesulfonamide

Suppliers and Price of N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide

Chemical Property:

Refractive Index:1.6270 (estimate)
PSA：141.16000
Density:1.532g/cm³
LogP:3.40900
Water Solubility.:0.41g/L(37 oC)
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:312.03508260
Heavy Atom Count:20
Complexity:443

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C

Technology Process of N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide

There total 5 articles about N-(4-(((5-Methyl-1,3,4-thiadiazol-2-yl)amino)sulphonyl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 108-33-8
5-methyl-1,3,4-thiadiazol-2-amine

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 39719-87-4
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide

Guidance literature:: With pyridine; at 95 ℃; for 1h;
DOI:10.1016/j.bmc.2011.01.049

Reference yield: 30.3%

: 144-82-1
sulfamethizole

: 75-36-5
acetyl chloride

: 39719-87-4
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide

Guidance literature:: In pyridine; at 20 ℃; for 2h;

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 39719-87-4
N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane; pyridine / 2 h / 20 °C

2: hydrogenchloride / iron / ethanol; water / 3 h / Reflux

3: pyridine / 2 h / 20 °C

With hydrogenchloride; iron; In pyridine; ethanol; dichloromethane; water;