1-(3-Chlorophenyl)-3-(4-fluorophenyl)urea

Base Information

Chemical Name:1-(3-Chlorophenyl)-3-(4-fluorophenyl)urea
CAS No.:13208-44-1
Molecular Formula:C13H10ClFN2O
Molecular Weight:264.6827
Hs Code.:
European Community (EC) Number:666-496-1
NSC Number:104504
DSSTox Substance ID:DTXSID00295712
Wikidata:Q82035799
ChEMBL ID:CHEMBL1688070

Synonyms:1-(3-chlorophenyl)-3-(4-fluorophenyl)urea;13208-44-1;NSC104504;Cambridge id 5273117;CHEMBL1688070;SCHEMBL11007034;DTXSID00295712;AKOS002262319;NSC-104504;AB00078587-01;SR-01000202813;SR-01000202813-1

Suppliers and Price of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)urea

Chemical Property:

Vapor Pressure:0.00234mmHg at 25°C
Boiling Point:288.4°Cat760mmHg
Flash Point:128.2°C
Density:1.422g/cm³
XLogP3:4.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:264.0465688
Heavy Atom Count:18
Complexity:282

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)NC(=O)NC2=CC=C(C=C2)F

Technology Process of 1-(3-Chlorophenyl)-3-(4-fluorophenyl)urea

There total 3 articles about 1-(3-Chlorophenyl)-3-(4-fluorophenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1195-45-5
para-fluorophenyl isocyanate

: 108-42-9
3-chloro-aniline

: 13208-44-1
1-(3-chlorophenyl)-3-(4-fluorophenyl)urea

Guidance literature:: In dichloromethane; at 25 ℃; for 48h;

Reference yield:

: 371-40-4
4-fluoroaniline

: 2909-38-8
m-chlorophenyl isocyanate

: 13208-44-1
1-(3-chlorophenyl)-3-(4-fluorophenyl)urea

Guidance literature:: In dimethyl sulfoxide; at 20 ℃;
DOI:10.1021/ml100083c

Reference yield:

: 371-40-4
4-fluoroaniline

: 13208-44-1
1-(3-chlorophenyl)-3-(4-fluorophenyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / tetrahydrofuran / 12 h / 0 - 25 °C

1.2: 1 h / 0 °C

2.1: dichloromethane / 48 h / 25 °C

With triethylamine; In tetrahydrofuran; dichloromethane;