Epiborneol

Base Information

• Chemical Name: Epiborneol
• CAS No.: 1686-28-8
• Molecular Formula: C10H18 O
• Molecular Weight: 154.252
• Hs Code.: 2906199090
• Mol file: 1686-28-8.mol

Synonyms:3-Bornanol,endo- (8CI); Bicyclo[2.2.1]heptan-2-ol, 4,7,7-trimethyl-, endo-; Epiborneol;endo-4,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol; epi-Borneol

Chemical Property of Epiborneol

Chemical Property:

• Vapor Pressure: 0.0693mmHg at 25°C
• Boiling Point: 202.9°Cat760mmHg
• Flash Point: 80.7°C
• PSA: 20.23000
• Density: 0.992g/cm³
• LogP: 2.19350

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Epiborneol

There total 10 articles about Epiborneol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

tert-Butyl-dimethyl-((1R,2S,4R)-4,7,7-trimethyl-bicyclo[2.2.1]hept-2-yloxy)-silane → (+/-)-Epiborneol (1686-28-8)

Guidance literature:

With iodine; In methanol; for 3h; Heating;

DOI:10.1039/cc9960002351

Reference yield:

→ (+/-)-Epiborneol (1686-28-8) + 1,7,7-trimethyl bicyclo[2.2.1]heptan-2-ol (507-70-0)

Guidance literature:

With nitric acid; pentane; Behandeln des Reaktionsprodukts mit wss.-aethanol. Salzsaeure und Zink;

Reference yield:

(+/-)-epicamphor (53702-18-4) → (+/-)-Epiborneol (1686-28-8) + (+/-)-epi-isoborneol (1686-27-7,1686-28-8,22336-76-1,22553-62-4,24326-33-8,28974-20-1,33016-93-2,63976-53-4,63976-54-5)

Guidance literature:

With zirconium dioxide hydrate; isopropyl alcohol; at 130 ℃; for 1.25h; Overall yield = 73 %;

DOI:10.1021/ol400856g

upstream raw materials:

endo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl acetate

endo-bornyl acetate

(+/-)-epicamphor

acetic acid

Downstream raw materials:

4,7,7-Trimethyl-bicyclo[2.2.1]heptan-2-one

2,2-dimethyl-cyclopentane-1,1,3-tricarboxylic acid

Refernces

• 1、 Vaino, Andrew R.,Szarek, Walter A.. "A mild and efficient method for the deprotection of tert-butyldimethylsilyl ethers using iodine in methanol". . p. 2351 - 2352. Retrieved 2007/10/03.