Norletimol

Base Information

• Chemical Name: Norletimol
• CAS No.: 886-08-8
• Molecular Formula: C14H13 N O
• Molecular Weight: 211.263
• Mol file: 886-08-8.mol

Synonyms:Phenol,o-(N-benzylformimidoyl)- (6CI,7CI,8CI); 2-(Benzylformimidoyl)phenol;Benzyl(2-hydroxybenzylidene)amine; N-(2-Hydroxybenzylidene)benzylamine; NSC128931; Norletimol; Saddamine; Salicylaldehyde benzylamine imine;Salicylaldehyde benzylimine; Salicylidene benzylhydrazone;Salicylidenebenzylamine

Chemical Property of Norletimol

Chemical Property:

• Vapor Pressure: 3.65E-06mmHg at 25°C
• Boiling Point: 386°C at 760 mmHg
• Flash Point: 158.1°C
• PSA: 32.59000
• Density: 1.198g/cm³
• LogP: 3.01130

Purity/Quality:

99%min ^*data from raw suppliers

NORLETIMOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Norletimol

There total 9 articles about Norletimol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

salicylaldehyde (90-02-8) + benzylamine (100-46-9) → N-(benzyl)salicylaldimine (886-08-8)

Guidance literature:

With magnesium sulfate; In toluene; for 4h; Inert atmosphere; Reflux;

DOI:10.1039/c8dt02140f

Reference yield: 93.0%

salicylic alcohol (90-01-7) + benzylamine (100-46-9) → N-(benzyl)salicylaldimine (886-08-8)

Guidance literature:

With oxygen; sodium hydroxide; In tetrahydrofuran; 2,2,2-trifluoroethanol; at 30 ℃; for 12h;

DOI:10.1039/c2cc36213a

Reference yield:

(E)-2-((benzylideneamino)methyl)phenol + benzylamine (100-46-9) → N-(benzyl)salicylaldimine (886-08-8) + N-(2-hydroxybenzyl)salicylaldimine (3946-40-5) + (E)-N-benzylidenebenzylamine (27845-50-7)

Guidance literature:

With Quinuclidine; zinc dibromide; In acetonitrile; at 50 ℃; for 48h; Molecular sieve; Inert atmosphere;

DOI:10.1002/chem.201500520

upstream raw materials:

salicylaldehyde

benzylamine

ethyl N-salicylideneglycinate

N-phenylsalicylaldimine

Downstream raw materials:

[Benzylamino-(2-hydroxy-phenyl)-methyl]-phosphonic acid diethyl ester

[N-benzyl(salicylideneimine(N,O)),N-benzyl(salicylideneimine(C,N,O))]-(triphenylphosphine)ruthenium(III)

bis-[N-benzyl(salicylideneimine)]bis-(triphenylphosphine)ruthenium(II)

2-((N-benzylpyrid-2-ylmethylamino)methyl)phenol

Refernces

• 1、 Tavernier, Romain,Granado, Lérys,Foyer, Gabriel,David, Ghislain,Caillol, Sylvain. "Formaldehyde-Free Polybenzoxazines for High Performance Thermosets". . p. 2557 - 2567. Retrieved 2020/04/10.
• 2、 Daneshmand, Pargol,Pinon, Leena,Schaper, Frank. "Dinuclear iminophenoxide copper complexes in rac-lactide polymerisation". . p. 10147 - 10161. Retrieved 2018/08/09.