2,4-Diaminopentanedioic acid

Base Information

• Chemical Name: 2,4-Diaminopentanedioic acid
• CAS No.: 1421-04-1
• Molecular Formula: C₅H₁₀N₂O₄
• Molecular Weight: 162.145
• Hs Code.: 2922499990
• NSC Number: 58391
• DSSTox Substance ID: DTXSID10931331
• Nikkaji Number: J2.111.868K
• Mol file: 1421-04-1.mol

Synonyms:2,4-diaminopentanedioic acid;1421-04-1;4-aminoglutamic acid;DL-2,4-Diaminoglutaric acid;NSC58391;2,4-diaminoglutaric acid;2,4-diaminopentanedioicacid;SCHEMBL600881;2,4-diamino-pentanedioic acid;DL-2,4-Diamino glutaric acid;DTXSID10931331;NSC-58391;AKOS006272461;FT-0692409

Chemical Property of 2,4-Diaminopentanedioic acid

Chemical Property:

• Vapor Pressure: 3.28E-07mmHg at 25°C
• Refractive Index: 1.565
• Boiling Point: 391.2 °C at 760 mmHg
• Flash Point: 190.4 °C
• PSA: 126.64000
• Density: 1.495 g/cm³
• LogP: -0.39910
• XLogP3: -6.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 162.06405680
• Heavy Atom Count: 11
• Complexity: 152

Purity/Quality:

99%, ^*data from raw suppliers

DL-2,4-DIAMINOGLUTARIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(C(=O)O)N)C(C(=O)O)N

Technology Process of 2,4-Diaminopentanedioic acid

There total 9 articles about 2,4-Diaminopentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2,4-diaminopentanedioic acid (1421-04-1)

Guidance literature:

With ethanol; nickel; at 60 - 115 ℃; under 183877 Torr; Hydrogenation_.Kochen des Reaktionsprodukts mit wss.HCl;

Reference yield:

(S,S)-2,4-Diamino-(E)-pentane-1,5-dioic acid dimethyl ester (758651-62-6) → 2,4-diaminopentanedioic acid (1421-04-1)

Guidance literature:

With pyridine; In ethanol; water;

DOI:10.1007/BF02494371

Reference yield:

2,4-Bis-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-pentanedioic acid dimethyl ester → 2,4-diaminopentanedioic acid (1421-04-1)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / H₂O / 9 h / Heating

2: 0.49 g / pyridine / ethanol; H₂O

With pyridine; hydrogenchloride; In ethanol; water;

DOI:10.1007/BF02494371

upstream raw materials:

(2-acetylamino-2,2-bis-ethoxycarbonyl-ethyl)-trimethyl-ammonium; iodide

2-acetylaminomalonic acid diethyl ester

2,4-Bis-acetamino-glutarsaeure-monoethylester

formaldehyd

Downstream raw materials:

2-Amino-4-(4-methylamino-benzoylamino)-pentanedioic acid diisopropyl ester

2-Amino-4-[4-(benzyloxycarbonyl-methyl-amino)-benzoylamino]-pentanedioic acid diisopropyl ester

2-Amino-4-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid diisopropyl ester

trans-4,6-dicarboxy-3,4,5,6-tetrahydropyrimidin-2(1H)-one

Refernces

• 1、 Tsushima,Kawada,Ishihara,Uchida,Shiratori,Higaki,Hirata. "Fluorine-ocntaining amino acids and their derivatives. 7.1 Synthesis and antitumor activity α- and γ-substituted methotrexate analogs". . p. 5375 - 5387. Retrieved 2007/10/02.