Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide

Base Information

• Chemical Name: Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide
• CAS No.: 162881-26-7
• Deprecated CAS: 725253-72-5,868272-78-0,856258-48-5,2177253-08-4,2387537-12-2
• Molecular Formula: C26H27O3P
• Molecular Weight: 418.472
• Hs Code.: 29319090
• European Community (EC) Number: 423-340-5,605-307-9
• UNII: JOV61FMS35
• DSSTox Substance ID: DTXSID8044597
• Nikkaji Number: J1.013.677F
• Wikidata: Q27281613
• ChEMBL ID: CHEMBL3182971
• Mol file: 162881-26-7.mol

Synonyms:162881-26-7;Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide;(phenylphosphoryl)bis(mesitylmethanone);Phosphine oxide, phenylbis(2,4,6-trimethylbenzoyl)-;Bis-trimethylbenzoyl phenylphosphine oxide;UNII-JOV61FMS35;phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide;JOV61FMS35;[phenyl-(2,4,6-trimethylbenzoyl)phosphoryl]-(2,4,6-trimethylphenyl)methanone;DTXSID8044597;C26H27O3P;Methanone, 1,1'-(phenylphosphinylidene)bis(1-(2,4,6-trimethylphenyl)-;EC 423-340-5;bis(2,4,6-trimethylbenzoyl)phenylphosphine oxide;(Phenylphosphoryl)bis[(2,4,6-trimethylphenyl)methanone];(PHENYLPHOSPHORYL)BIS((2,4,6-TRIMETHYLPHENYL)METHANONE);IRGACURE 801;SCHEMBL15158;C24H42O4S.xH3N;CHEMBL3182971;DTXCID6024597;Tox21_302690;C26-H27-O3-P;MFCD01863675;AKOS015896257;C24-H42-O4-S.x-H3-N;CS-W009691;NCGC00256655-01;AS-10624;CAS-162881-26-7;FT-0656698;I-819;P2312;D78117;phenylbis(2,4,6-trimethylbenzoyl)phosphineoxide;bis(2,4,6-trimethylbenzoyl)-phenylphosphineoxide;A810419;bis(2,4,6-trimethylbenzoyl)-phenylphosphine oxide;phenyl bis(2,4,6-trimethylbenzoyl)phosphine oxide;bis (2,4,6-trimethylbenzoyl)-phenylphosphine oxide;bis(2,4,6-trimethylbenzoyl)-phenyl phosphine oxide;bis(2,4,6-trimethylbenzoyl)-phenyl-phosphine oxide;Q27281613;BIS-TRIMETHYLBENZOYL PHENYLPHOSPHINE OXIDE [INCI];Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide, 97%, powder;Metanona, 1,1'-(fenilfosfinilideno)bis[1-(2,4,6-trimetilfenil)-

Chemical Property of Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide

Chemical Property:

• Vapor Pressure: 6.78E-14mmHg at 25°C
• Melting Point: 131-135 °C
• Refractive Index: 1.588
• Boiling Point: 589.968 °C at 760 mmHg
• Flash Point: 310.602 °C
• PSA: 61.02000
• Density: 1.173 g/cm³
• LogP: 6.20620
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: acetone, acetonitrile, toluene, and hexanedioldiacrylate: solubl
• Water Solubility.: acetone, acetonitrile, toluene, and hexanedioldiacrylate: soluble
• XLogP3: 6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 418.16978172
• Heavy Atom Count: 30
• Complexity: 610

Purity/Quality:

98% ^*data from raw suppliers

Phenylbis(2,4,6-trimethylbenzoyl)phosphine Oxide >96.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43-53
• Safety Statements: 22-24-37-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)C)C(=O)P(=O)(C2=CC=CC=C2)C(=O)C3=C(C=C(C=C3C)C)C)C
• Uses: Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide is a useful research chemical compound. 3-Bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid is a useful building block and has been used in the synthesis of the pesticide Cyclaniliprole. Versatile UV photoinitiator for radical polymerization of unsaturated resins, especially pigmented formulations.

Technology Process of Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide

There total 22 articles about Phenylbis(2,4,6-trimethylbenzoyl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

bis-(2,4,6-trimethylbenzoyl)-phenylphosphine (620596-61-4) → phenyl bis(2,4,6-trimethylbenzoyl)phosphine oxide (162881-26-7)

Guidance literature:

With Nitrogen dioxide; In toluene; for 1.5h; Inert atmosphere;

Reference yield: 91.0%

Dichlorophenylphosphine (644-97-3) + mesitylene-2-carboxylic acid chloride (938-18-1) → phenyl bis(2,4,6-trimethylbenzoyl)phosphine oxide (162881-26-7)

Guidance literature:

Dichlorophenylphosphine; With sodium amalgam; In toluene; for 1h; Reflux; Inert atmosphere;

With tert-butyl alcohol; In toluene; for 1h; Inert atmosphere; Reflux;

mesitylene-2-carboxylic acid chloride; In toluene; at 40 ℃; for 1h; Reagent/catalyst; Inert atmosphere;

Reference yield: 89.0%

C26H31O3P → phenyl bis(2,4,6-trimethylbenzoyl)phosphine oxide (162881-26-7)

Guidance literature:

With vanadium(IV) bis(2,4-pentanedionate); dihydrogen peroxide; at 20 ℃; for 16.5h; Reagent/catalyst;

upstream raw materials:

mesitylene-2-carboxylic acid chloride

bis-(2,4,6-trimethylbenzoyl)-phenylphosphine

P,P-dichlorophenylphosphine oxide

Dichlorophenylphosphine

Downstream raw materials:

mesytaldehyde

4-Oxo-4-<2,4,6-trimethyl-phenyl>-but-2-ensaeure-butylester

Refernces

• 1、 -. "Preparation method of bis(2,4,6-trimethylbenzoyl)phenyl phosphine oxide". Paragraph 0100-0102; 0107-0109; 0115-0117; 0122-0193. . Retrieved 2021/01/11.
• 2、 -. "Preparation method of photoinitiator". Paragraph 0053-0060. . Retrieved 2021/03/24.