2,4-Dimethoxy-6-phenyl-1,3,5-triazine

Base Information

• Chemical Name: 2,4-Dimethoxy-6-phenyl-1,3,5-triazine
• CAS No.: 18213-73-5
• Molecular Formula: C11H11 N3 O2
• Molecular Weight: 217.227
• Hs Code.: 2933699090
• DSSTox Substance ID: DTXSID00274865
• Nikkaji Number: J1.557.283C
• Wikidata: Q82004344
• Mol file: 18213-73-5.mol

Synonyms:2,4-dimethoxy-6-phenyl-1,3,5-triazine;18213-73-5;2,4-DIMETHOXY-6-PHENYL-S-TRIAZINE;SCHEMBL1130501;DTXSID00274865;MBOHQAALDUADLU-UHFFFAOYSA-N;2-phenyl-4,6-dimethoxy-1,3,5-triazine;FT-0766303;1-Methyl-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride?

Chemical Property of 2,4-Dimethoxy-6-phenyl-1,3,5-triazine

Chemical Property:

• Vapor Pressure: 1.2E-05mmHg at 25°C
• Boiling Point: 380.3°C at 760 mmHg
• Flash Point: 138.3°C
• PSA: 57.13000
• Density: 1.19g/cm³
• LogP: 1.55580
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 217.085126602
• Heavy Atom Count: 16
• Complexity: 197

Purity/Quality:

99.3% ^*data from raw suppliers

2,4-DIMETHOXY-6-PHENYL-1,3,5-TRIAZINE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=NC(=NC(=N1)C2=CC=CC=C2)OC

Technology Process of 2,4-Dimethoxy-6-phenyl-1,3,5-triazine

There total 12 articles about 2,4-Dimethoxy-6-phenyl-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-chloro-4,6-dimethoxy-1 ,3,5-triazine (3140-73-6) → 2,4-dimethoxy-6-phenyl-1,3,5-triazine (18213-73-5)

Guidance literature:

PhMgX; With zinc(II) chloride;

2-chloro-4,6-dimethoxy-1 ,3,5-triazine; With isopropylmagnesium chloride; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 2h;

DOI:10.1016/j.tet.2005.02.085

Reference yield: 89.0%

2-chloro-4,6-dimethoxy-1 ,3,5-triazine (3140-73-6) + phenylboronic acid (98-80-6) → 2,4-dimethoxy-6-phenyl-1,3,5-triazine (18213-73-5)

Guidance literature:

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; [di(cyclohexyl)phosphino]bis(2-pyrimidyl)amine; In 1,4-dioxane; at 60 ℃; for 24h;

DOI:10.1002/1521-3773(20020503)41:9<1521::AID-ANIE1521>3.0.CO;2-R

Reference yield: 75.0%

2-chloro-4,6-dimethoxy-1 ,3,5-triazine (3140-73-6) + triphenylaluminium (841-76-9) → 2,4-dimethoxy-6-phenyl-1,3,5-triazine (18213-73-5)

Guidance literature:

bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; diethyl ether; for 12h; Heating;

DOI:10.1016/j.tet.2005.02.085

upstream raw materials:

methanol

2,4-dichloro-6-phenyl-1,3,5-triazine

2-chloro-4,6-dimethoxy-1 ,3,5-triazine

phenylboronic acid