2-Iodophenyl acetate

Base Information

• Chemical Name: 2-Iodophenyl acetate
• CAS No.: 32865-61-5
• Molecular Formula: C8H7 I O2
• Molecular Weight: 262.047
• Hs Code.: 2915390090
• European Community (EC) Number: 608-794-6
• DSSTox Substance ID: DTXSID50186520
• Nikkaji Number: J323.604H
• Wikidata: Q83057827
• Mol file: 32865-61-5.mol

Synonyms:2-iodophenyl acetate;32865-61-5;1-Acetoxy-2-iodobenzene;(2-iodophenyl) acetate;Phenol, 2-iodo-, acetate;2-iodophenylacetate;iodophenol acetate;Phenol,2-iodo-,acetate;(2-iodanylphenyl) ethanoate;SCHEMBL177166;DTXSID50186520;acetic acid (2-iodophenyl) ester;MFCD07780625;AKOS005070588;CS-0188298;FT-0680420;E78495;4Y-0965;A821473;Ethyl2-(4-bromophenyl)-1,3-oxazole-4-carboxylate;J-509732

Chemical Property of 2-Iodophenyl acetate

Chemical Property:

• Vapor Pressure: 0.00588mmHg at 25°C
• Boiling Point: 273°Cat760mmHg
• Flash Point: 118.9°C
• PSA: 26.30000
• Density: 1.757g/cm³
• LogP: 2.21650
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 261.94908
• Heavy Atom Count: 11
• Complexity: 147

Purity/Quality:

97% ^*data from raw suppliers

2-IodophenylAcetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC1=CC=CC=C1I

Technology Process of 2-Iodophenyl acetate

There total 7 articles about 2-Iodophenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-Iodophenol (533-58-4) + acetic anhydride (108-24-7) → 2-iodophenyl acetate (32865-61-5)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1021/ol2032009

Reference yield: 97.0%

2-Iodophenol (533-58-4) + acetyl chloride (75-36-5) → 2-iodophenyl acetate (32865-61-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; dichloromethane; at 20 ℃; for 5h;

DOI:10.1021/ol000087t

Reference yield: 78.0%

O-acetylsalicyloyl chloride (5538-51-2) → 2-iodophenyl acetate (32865-61-5)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In o-xylene; at 150 ℃; for 12h;

DOI:10.1038/s41557-018-0078-8

upstream raw materials:

2-Iodophenol

acetic anhydride

o-(Trimethylsilyl)phenyl Acetate

carbon monoxide

Downstream raw materials:

4'-hydroxy-3'-iodoacetophenone

acetic acid-(2-dichloroiodanyl-phenyl ester)

benzyl 2(S)-<(tert-butoxycarbonyl)amino>-3-(2'-acetoxyphenyl)propionate

2-phenylbenzofuran