N-(2-Ethylphenyl)benzamide

Base Information

• Chemical Name: N-(2-Ethylphenyl)benzamide
• CAS No.: 78987-16-3
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• NSC Number: 77045
• DSSTox Substance ID: DTXSID10291664
• Nikkaji Number: J1.424.107H
• Wikidata: Q82029680
• Mol file: 78987-16-3.mol

Synonyms:N-(2-Ethylphenyl)benzamide;78987-16-3;NSC77045;SCHEMBL528445;N-(2-Ethylphenyl)benzamide #;Benzamide, N-(2-ethylphenyl)-;DTXSID10291664;Benzamide, N-(2'-ethylphenyl)-;NSDKDLAEYFSRJC-UHFFFAOYSA-N;NSC-77045;STL387902;AKOS000611996;CS-0367704;AG-690/11171140;SR-01000369509;SR-01000369509-1

Chemical Property of N-(2-Ethylphenyl)benzamide

Chemical Property:

• Vapor Pressure: 0.00346mmHg at 25°C
• Boiling Point: 281.9°Cat760mmHg
• Flash Point: 167.3°C
• PSA: 29.10000
• Density: 1.12g/cm³
• LogP: 3.57430
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 225.115364102
• Heavy Atom Count: 17
• Complexity: 245

Purity/Quality:

99% ^*data from raw suppliers

BENZAMIDE,N-(2-ETHYLPHENYL)- 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC=CC=C1NC(=O)C2=CC=CC=C2

Technology Process of N-(2-Ethylphenyl)benzamide

There total 10 articles about N-(2-Ethylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

→ 2'-Ethylbenzanilide (78987-16-3)

Guidance literature:

With tetrabutylammomium bromide; caesium carbonate; In water; for 0.333333h; Microwave irradiation;

Reference yield: 90.0%

N-(2-ethylphenyl)-N-((tosylimino)methyl)benzamide → 2'-Ethylbenzanilide (78987-16-3)

Guidance literature:

With methanol; potassium carbonate; at 20 ℃; for 1h; Reagent/catalyst; Solvent; Temperature;

DOI:10.1021/ol5031876

Reference yield: 81.0%

ortho-ethylaniline (578-54-1) + N,N-dimethylbenzamide (611-74-5) → 2'-Ethylbenzanilide (78987-16-3)

Guidance literature:

With potassium tert-butylate; In diethylene glycol dimethyl ether; at 110 ℃; for 0.666667h; Inert atmosphere; Microwave irradiation;

DOI:10.1002/ejoc.201900666

upstream raw materials:

ortho-ethylaniline

benzoyl chloride

2'-acetylbenzanilide

benzoic acid anhydride

Downstream raw materials:

N-benzyl-2-ethylaniline

N-(2-ethylphenyl)thiobenzamide

2-phenyl-3-methyl-1H-indole

Refernces

• 1、 -. "Method for synthesizing amide compound through photocatalysis in water phase". Paragraph 0061-0067. . Retrieved 2019/10/01.
• 2、 Ran, Rui-Qiao,Xiu, Shi-Dong,Li, Chuan-Ying. "Synthesis of N -acylamidines via rhodium-catalyzed reaction of nitrosobenzene derivatives with N -sulfonyl-1,2,3-triazoles". . p. 6394 - 6396. Retrieved 2015/02/18.