N-(2-Acetylphenyl)benzamide

Base Information

• Chemical Name: N-(2-Acetylphenyl)benzamide
• CAS No.: 6011-26-3
• Molecular Formula: C15H13NO2
• Molecular Weight: 239.274
• DSSTox Substance ID: DTXSID90208856
• Nikkaji Number: J676.009K
• Wikidata: Q83083007
• Mol file: 6011-26-3.mol

Synonyms:N-(2-Acetylphenyl)benzamide;Benzamide, N-(2-acetylphenyl)-;6011-26-3;Benzamido-2 acetophenone;Benzamido-2 acetophenone [French];Benzanilide, 2'-acetyl-;N-(2-acetyl-phenyl)-benzamide;SCHEMBL15233661;DTXSID90208856;AKOS000192295;CCG-298016;LS-25247;A1-05895;Z27879779

Chemical Property of N-(2-Acetylphenyl)benzamide

Chemical Property:

• Vapor Pressure: 0.000477mmHg at 25°C
• Boiling Point: 314.1°Cat760mmHg
• Flash Point: 110.3°C
• PSA: 49.66000
• Density: 1.197g/cm³
• LogP: 3.52550
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 239.094628657
• Heavy Atom Count: 18
• Complexity: 308

Purity/Quality:

95% ^*data from raw suppliers

N-(2-Acetylphenyl)benzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC=CC=C1NC(=O)C2=CC=CC=C2

Technology Process of N-(2-Acetylphenyl)benzamide

There total 34 articles about N-(2-Acetylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-aminoacetophenone (551-93-9) + benzoyl chloride (98-88-4) → 2'-acetylbenzanilide (6011-26-3)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1002/chem.201504749

Reference yield: 100.0%

3-hydroxy-3-methyl-2-phenyl-3H-indole-1-oxide (57309-13-4) → 2'-acetylbenzanilide (6011-26-3)

Guidance literature:

In acetonitrile; for 0.333333h; Inert atmosphere; UV-irradiation;

DOI:10.1016/j.tet.2011.06.094

Reference yield: 96.0%

N-(2-((E)-1-(((E)-1-phenylethylidene)hydrazono)ethyl)phenyl)benzamide → 2'-acetylbenzanilide (6011-26-3)

Guidance literature:

With hydrogenchloride; water; In dichloromethane; at 20 ℃;

DOI:10.1016/j.cclet.2020.08.046

upstream raw materials:

3-hydroperoxy-3-methyl-2-phenyl-3H-indole

5-methyl-2-phenyl-1,5-dihydro-2H-2,5-epoxido-benzo[e][1,2,4]dioxazepine

toluene-4-sulfonic acid

acetic acid

Downstream raw materials:

2-phenyl-3-methyl-1H-indole

1-(2'-Benzamidophenyl)ethanol

N-[2-(2,2,2-Trichloro-acetyl)-phenyl]-benzimidoyl chloride

4-methyl-2-phenyl-3,4-dihydroquinazoline