Propionic acid, 3,3'-diselenodi-

Base Information

• Chemical Name: Propionic acid, 3,3'-diselenodi-
• CAS No.: 7370-58-3
• Molecular Formula: C6H10O4Se2
• Molecular Weight: 304.063
• European Community (EC) Number: 621-993-2
• UNII: 2SP2QS73W9
• DSSTox Substance ID: DTXSID40224006
• Nikkaji Number: J122.232E
• Wikidata: Q83102519
• Mol file: 7370-58-3.mol

Synonyms:3,3'-diselenodipropionic acid;DSePA cpd

Chemical Property of Propionic acid, 3,3'-diselenodi-

Chemical Property:

• Melting Point: 134.5-135.5 °C
• Boiling Point: 493.1°Cat760mmHg
• PKA: 3.94±0.10(Predicted)
• Flash Point: 252°C
• PSA: 74.60000
• Density: g/cm³
• LogP: 0.09580
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 305.89095
• Heavy Atom Count: 12
• Complexity: 142

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C[Se][Se]CCC(=O)O)C(=O)O

Technology Process of Propionic acid, 3,3'-diselenodi-

There total 8 articles about Propionic acid, 3,3'-diselenodi- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-Bromopropionic acid (590-92-1) → 3,3'-diselenodipropanoic acid (7370-58-3)

Guidance literature:

With sodium diselenide; In water; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/ejoc.201500124

Reference yield: 81.3%

chloropropionic acid (107-94-8) → 3,3'-diselenodipropanoic acid (7370-58-3)

Guidance literature:

With selenium; sodium tetrahydroborate; In water; at 25 ℃; for 16h;

DOI:10.1039/d0tb02192j

Reference yield:

chloropropionic acid (107-94-8) + sodium diselenide → 3,3'-diselenodipropanoic acid (7370-58-3)

Guidance literature:

at 20 ℃; for 4h; pH=8; Inert atmosphere;

DOI:10.1016/j.ijpharm.2019.118486

upstream raw materials:

β-Propiolactone

3-selenocyanatopropanoic acid

hydrogenchloride

3-Bromopropionic acid

Downstream raw materials:

C₁₈H₂₂N₄O₂Se₂

C₁₀H₁₀O₄SSe

4,4'-Dithiobisbenzoic acid

3-(4-Nitrobenzylseleno)propionsaeure

Refernces

• 1、 Xu, Jingwen,Yan, Xiangji,Ge, Xin,Zhang, Mingzhen,Dang, Xugang,Yang, Yan,Xu, Feng,Luo, Yanling,Li, Guoliang. "Novel multi-stimuli responsive functionalized PEG-based co-delivery nanovehicles toward sustainable treatments of multidrug resistant tumor". . p. 1297 - 1314. Retrieved 2021.
• 2、 -. "NIR responsive cross-linked micelles, drug delivery carrier targeting cancer cell and method for preparing the same". Paragraph 0192-0194. . Retrieved 2020/07/28.