3-Chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Base Information

Chemical Name:3-Chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone
CAS No.:125974-08-5
Molecular Formula:C₅H₄Cl₂O₃
Molecular Weight:182.991
Hs Code.:
DSSTox Substance ID:DTXSID70925337
Nikkaji Number:J313.415F
Mol file:125974-08-5.mol

Synonyms:3-CCMHF;3-chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone;CMCF cpd

Suppliers and Price of 3-Chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-CHLORO-4-(CHLOROMETHYL)-5-HYDROXY-2(5H)-FURANONE 95.00%
5MG
$ 499.08

Total 3 raw suppliers

Chemical Property of 3-Chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Chemical Property:

Vapor Pressure:4.83E-08mmHg at 25°C
Boiling Point:399.5°Cat760mmHg
Flash Point:195.4°C
PSA：46.53000
Density:1.65g/cm³
LogP:0.59330
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:181.9537494
Heavy Atom Count:10
Complexity:199

Purity/Quality:

99% ^*data from raw suppliers

3-CHLORO-4-(CHLOROMETHYL)-5-HYDROXY-2(5H)-FURANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(C1=C(C(=O)OC1O)Cl)Cl

Technology Process of 3-Chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

There total 6 articles about 3-Chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80904-75-2
4-hydroxymethyl-5H-furan-2-one

: 125974-08-5
3-chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Guidance literature:: Multi-step reaction with 5 steps

1: 8 percent / Ph₃P, CCl₄ / 72 h / 25 °C

2: AlCl₃, Cl₂ / CH₂Cl₂ / 16 h / 20 - 25 °C

3: NEt₃ / CH₂Cl₂ / 0 °C

4: 450 mg / NBS / CCl₄ / 0.58 h / Irradiation

5: silver acetate / acetone; H₂O / 96 h

With tetrachloromethane; N-Bromosuccinimide; aluminium trichloride; silver(I) acetate; chlorine; triethylamine; triphenylphosphine; In tetrachloromethane; dichloromethane; water; acetone;
DOI:10.1021/jo00296a053

Reference yield:

: 125974-04-1
5-Bromo-3-chloro-4-chloromethyl-5H-furan-2-one

: 125974-08-5
3-chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Guidance literature:: With silver(I) acetate; In water; acetone; for 96h; Yield given;
DOI:10.1021/jo00296a053

Reference yield:

: 125973-99-1
4-(Chloromethyl)-2(5H)-furanone

: 125974-08-5
3-chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Guidance literature:: Multi-step reaction with 4 steps

1: AlCl₃, Cl₂ / CH₂Cl₂ / 16 h / 20 - 25 °C

2: NEt₃ / CH₂Cl₂ / 0 °C

3: 450 mg / NBS / CCl₄ / 0.58 h / Irradiation

4: silver acetate / acetone; H₂O / 96 h

With N-Bromosuccinimide; aluminium trichloride; silver(I) acetate; chlorine; triethylamine; In tetrachloromethane; dichloromethane; water; acetone;
DOI:10.1021/jo00296a053