3-Chloro-4-(chloromethyl)-2(5H)-furanone

Base Information

Chemical Name:3-Chloro-4-(chloromethyl)-2(5H)-furanone
CAS No.:125974-01-8
Molecular Formula:C₅H₄Cl₂O₂
Molecular Weight:166.992
Hs Code.:
UNII:W82W6QNR5H
DSSTox Substance ID:DTXSID30155017
Nikkaji Number:J313.411C
Wikidata:Q83022586
Mol file:125974-01-8.mol

Synonyms:3-Chloro-4-(chloromethyl)-2(5H)-furanone;125974-01-8;4-chloro-3-(chloromethyl)-2H-furan-5-one;2(5H)-Furanone, 3-chloro-4-(chloromethyl)-;W82W6QNR5H;CCRIS 5337;UNII-W82W6QNR5H;DTXSID30155017;AKOS006279887

Suppliers and Price of 3-Chloro-4-(chloromethyl)-2(5H)-furanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-chloro-4-(chloromethyl)-2(5H)-Furanone 97.00%
25G
$ 7320.00

AccelPharmtech
3-chloro-4-(chloromethyl)-2(5H)-Furanone 97.00%
1G
$ 2280.00

Total 1 raw suppliers

Chemical Property of 3-Chloro-4-(chloromethyl)-2(5H)-furanone

Chemical Property:

Vapor Pressure:0.000611mmHg at 25°C
Boiling Point:310.1°Cat760mmHg
Flash Point:153.4°C
PSA：26.30000
Density:1.48g/cm³
LogP:1.27490
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.9588348
Heavy Atom Count:9
Complexity:174

Purity/Quality:: 3-chloro-4-(chloromethyl)-2(5H)-Furanone 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=C(C(=O)O1)Cl)CCl

Technology Process of 3-Chloro-4-(chloromethyl)-2(5H)-furanone

There total 4 articles about 3-Chloro-4-(chloromethyl)-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 6304-34-3
trichloro-acetic acid allyl ester

: 87223-92-5
3,3-dichloro-4-chloromethyl-4,5-dihydro-3H-furan-2-one

: 125974-01-8
3-Chloro-4-(chloromethyl)-2(5H)-furanone

Guidance literature:: C₂₇H₃₇N₂ClCu stable copper(I)-NHC complex; In 1,2-dichloro-ethane; at 110 ℃; for 17h; microwave irradiation;
DOI:10.1016/j.tetlet.2007.12.084

Reference yield:

: 3,4-Dichloro-4-chloromethyl-dihydro-furan-2-one

: 125974-01-8
3-Chloro-4-(chloromethyl)-2(5H)-furanone

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; Yield given;
DOI:10.1021/jo00296a053

Reference yield:

: 80904-75-2
4-hydroxymethyl-5H-furan-2-one

: 125974-01-8
3-Chloro-4-(chloromethyl)-2(5H)-furanone

Guidance literature:: Multi-step reaction with 3 steps

1: 8 percent / Ph₃P, CCl₄ / 72 h / 25 °C

2: AlCl₃, Cl₂ / CH₂Cl₂ / 16 h / 20 - 25 °C

3: NEt₃ / CH₂Cl₂ / 0 °C

With tetrachloromethane; aluminium trichloride; chlorine; triethylamine; triphenylphosphine; In dichloromethane;
DOI:10.1021/jo00296a053