1,4-Didodecylpiperazine

Base Information

• Chemical Name: 1,4-Didodecylpiperazine
• CAS No.: 82394-21-6
• Molecular Formula: C₂₈H₅₈N₂
• Molecular Weight: 422.782
• NSC Number: 28941
• DSSTox Substance ID: DTXSID70282952
• Nikkaji Number: J2.579.211D
• Wikidata: Q82017356
• Mol file: 82394-21-6.mol

Synonyms:1,4-didodecylpiperazine;82394-21-6;NSC28941;SCHEMBL4307534;1,4-DIDODECYL-PIPERAZINE;DTXSID70282952;NSC-28941;AKOS024428081

Chemical Property of 1,4-Didodecylpiperazine

Chemical Property:

• Vapor Pressure: 3.04E-10mmHg at 25°C
• Boiling Point: 502.9°Cat760mmHg
• Flash Point: 218.6°C
• Density: 0.856g/cm³
• XLogP3: 11.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 22
• Exact Mass: 422.459999859
• Heavy Atom Count: 30
• Complexity: 291

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCN1CCN(CC1)CCCCCCCCCCCC

Technology Process of 1,4-Didodecylpiperazine

There total 4 articles about 1,4-Didodecylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

piperazine (110-85-0) + 1-dodecylbromide (143-15-7) → 1,4-didodecylpiperazine (82394-21-6)

Guidance literature:

With potassium carbonate; at 100 - 110 ℃; for 1.5h; 150 deg C, 1 h;

DOI:10.1135/cccc19821130

Reference yield: 42.0%

piperazine (110-85-0) + 1-undecene (821-95-4) + carbon monoxide (201230-82-2) → 1,4-didodecylpiperazine (82394-21-6)

Guidance literature:

With dicarbonylacetylacetonato rhodium (I); hydrogen; 6,6′-[(3,3′-di-tert-butyl-5,5′-dimethoxy-1,1′-biphenyl-2,2′-diyl)bis(oxy)]bis(di-benzo[d,f][1,3,2]dioxaphosphepin); In toluene; at 120 ℃; for 16h; under 30003 Torr; Autoclave;

DOI:10.1002/adsc.201500896

Reference yield:

n-Dodecylamine (124-22-1) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → N,N'-didodecyl ethylenediamine (15411-40-2) + 1,4-didodecylpiperazine (82394-21-6)

Guidance literature:

DOI:10.1021/ja01179a510

upstream raw materials:

piperazine

1-Iodododecane

1-dodecylbromide

n-Dodecylamine