2-Nitro-5-chlorobenzofuran

Base Information

Chemical Name:2-Nitro-5-chlorobenzofuran
CAS No.:30335-66-1
Molecular Formula:C8H4 Cl N O3
Molecular Weight:197.578
Hs Code.:
NSC Number:170706
DSSTox Substance ID:DTXSID60305407
Nikkaji Number:J3.323.669G
Wikidata:Q82052035

Synonyms:NSC170706;30335-66-1;DTXSID60305407;NSC-170706

Suppliers and Price of 2-Nitro-5-chlorobenzofuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Nitro-5-chlorobenzofuran

Chemical Property:

Vapor Pressure:0.0011mmHg at 25°C
Boiling Point:310.4°Cat760mmHg
Flash Point:141.5°C
Density:1.518g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:196.9879707
Heavy Atom Count:13
Complexity:218

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Cl)C=C(O2)[N+](=O)[O-]

Technology Process of 2-Nitro-5-chlorobenzofuran

There total 5 articles about 2-Nitro-5-chlorobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 14268-23-6
potassium trinitromethanide

: 6296-65-7
1-(5-chloro-2-hydroxyphenyl)-N,N,N-trimethylmethanaminium iodide

: 30335-66-1
nitro-2 chloro-5 benzofuranne

Guidance literature:: With triethylamine; In acetonitrile; for 0.666667h; Inert atmosphere; Reflux;
DOI:10.1021/jo402543s

Reference yield:

: C₈H₈ClNO₃

: 30335-66-1
nitro-2 chloro-5 benzofuranne

Guidance literature:: With [bis(acetoxy)iodo]benzene; tetra-(n-butyl)ammonium iodide; triethylamine; In acetonitrile; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.chempr.2017.06.015

Reference yield:

: 61131-68-8
5-chloro-2-hydroxy-β-nitrostyrene

: 30335-66-1
nitro-2 chloro-5 benzofuranne

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate; methanol / 0 - 20 °C / Inert atmosphere

2: triethylamine; tetra-(n-butyl)ammonium iodide; [bis(acetoxy)iodo]benzene / acetonitrile / 2 h / 20 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; [bis(acetoxy)iodo]benzene; tetra-(n-butyl)ammonium iodide; triethylamine; In acetonitrile;
DOI:10.1016/j.chempr.2017.06.015