1-palmitoyl-2-thiopalmitoyl phosphatidylcholine

Base Information

• Chemical Name: 1-palmitoyl-2-thiopalmitoyl phosphatidylcholine
• CAS No.: 113881-60-0
• Molecular Formula: C₄₀H₈₀NO₇PS
• Molecular Weight: 750.117
• Mol file: 113881-60-0.mol

Synonyms:1-palmitoyl-2-thiopalmitoyl phosphatidylcholine

Chemical Property of 1-palmitoyl-2-thiopalmitoyl phosphatidylcholine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 137.07000
• Density: g/cm³
• LogP: 12.39860

Purity/Quality:

97% ^*data from raw suppliers

PalmitoylThio-phosphocholine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Palmitoyl Thio-phosphocholine is a highly specific chromogenic substrate of phospholipase A2.

Technology Process of 1-palmitoyl-2-thiopalmitoyl phosphatidylcholine

There total 2 articles about 1-palmitoyl-2-thiopalmitoyl phosphatidylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

C37H71BrO7PS(1-) + trimethylamine (75-50-3) → 2-thiophosphatidylcholine (113881-60-0)

Guidance literature:

In chloroform; acetonitrile; at 60 ℃; for 14h;

DOI:10.1016/S0040-4039(00)96379-2

Reference yield:

Hexadecanoic acid (R)-3-[(2-bromo-ethoxy)-chloro-phosphoryloxy]-2-hexadecanoylsulfanyl-propyl ester → 2-thiophosphatidylcholine (113881-60-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. KCl / 1 h

2: 52 percent / CHCl₃; acetonitrile / 14 h / 60 °C

With potassium chloride; In chloroform; acetonitrile;

DOI:10.1016/S0040-4039(00)96379-2

upstream raw materials:

trimethylamine

Refernces