(3-Bromophenyl)phenylmethanol

Base Information

• Chemical Name: (3-Bromophenyl)phenylmethanol
• CAS No.: 63012-04-4
• Molecular Formula: C13H11BrO
• Molecular Weight: 263.134
• European Community (EC) Number: 825-095-3
• NSC Number: 143362
• DSSTox Substance ID: DTXSID10301434
• Nikkaji Number: J594.813D
• Mol file: 63012-04-4.mol

Synonyms:(3-bromophenyl)(phenyl)methanol;(3-Bromophenyl)phenylmethanol;63012-04-4;(3-bromophenyl)-phenylmethanol;3-bromobenzhydrol;NSC143362;3-Bromobenzhydryl alcohol;SCHEMBL4678;DTXSID10301434;(3-Bromo-phenyl)-phenyl-methanol;MFCD00449886;AKOS008141454;NSC 143362;NSC-143362;NS-04105;FT-0766345;EN300-69391;Z513750188

Chemical Property of (3-Bromophenyl)phenylmethanol

Chemical Property:

• Vapor Pressure: 3.38E-06mmHg at 25°C
• Boiling Point: 372.2°Cat760mmHg
• Flash Point: 178.9°C
• Density: 1.435g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 261.99933
• Heavy Atom Count: 15
• Complexity: 189

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC(=CC=C2)Br)O

Technology Process of (3-Bromophenyl)phenylmethanol

There total 23 articles about (3-Bromophenyl)phenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

m-bromobenzoic aldehyde (3132-99-8) + phenylmagnesium bromide (100-58-3) → 3-bromobenzhydrol (63012-04-4)

Guidance literature:

In diethyl ether; for 1.5h; Heating;

Reference yield: 98.0%

m-bromobenzoic aldehyde (3132-99-8) + phenylmagnesium bromide → 3-bromobenzhydrol (63012-04-4)

Guidance literature:

In diethyl ether;

DOI:10.1021/ja00030a055

Reference yield: 92.0%

m-bromobenzoic aldehyde (3132-99-8) + phenylboronic acid (98-80-6) → 3-bromobenzhydrol (63012-04-4)

Guidance literature:

phenylboronic acid; With trimethyl gallium; In toluene; at 20 ℃; for 2h; Inert atmosphere;

m-bromobenzoic aldehyde; In toluene; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1055/s-0028-1087552

upstream raw materials:

3-bromobenzophenone

1,2-bis-(3-bromo-phenyl)-1,2-diphenyl-ethane-1,2-diol

Phenetole

m-bromobenzoic aldehyde

Downstream raw materials:

3-bromobenzophenone

(-)-(3-bromophenyl)phenylmethanol

bromodiphenhydramine

1-(3-benzylphenyl)ethan-1-one

Refernces

• 1、 Chen, Gong,Qiao, Tianjiao,Wang, Yaxin,Zhang, Jian,Zhao, Jianyou. "Tunable System for Electrochemical Reduction of Ketones and Phthalimides". supporting information. p. 3297 - 3302. Retrieved 2021/10/14.
• 2、 Winters, Maria,DuHadaway, James B.,Pham, Khoa N.,Lewis-Ballester, Ariel,Badir, Shorouk,Wai, Jenny,Sheikh, Eesha,Yeh, Syun-Ru,Prendergast, George C.,Muller, Alexander J.,Malachowski, William P.. "Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase". supporting information. p. 455 - 464. Retrieved 2018/11/25.