4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole

Base Information

Chemical Name:4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole
CAS No.:22091-36-7
Molecular Formula:C10H7 Cl2 N O
Molecular Weight:228.078
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70427927
Wikidata:Q82240674
Mol file:22091-36-7.mol

Synonyms:4-(chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole;22091-36-7;4-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)OXAZOLE;SCHEMBL202513;DTXSID70427927;BGGPUCCJQGIJRL-UHFFFAOYSA-N;MFCD07687118;AKOS001171791;AB42096;NCGC00335362-01;4-chloromethyl-2-(4-chlorophenyl)oxazole;2-(4-Chloro-phenyl)-4-Chloromethyloxazole;2-(4-chlorophenyl)-4-chloromethyl-oxazole;4-chloromethyl-2-(4-chlorophenyl) oxazole;4-Chloromethyl-2-(4-chloro-phenyl)-oxazole;EN300-15282;AB01328436-02;Z125140224;2-HYDROXY-3-(4-METHOXY-PHENYL)-3-(2-NITRO-PHENYLSULFANYL)-PROPIONICACID

Suppliers and Price of 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole
50mg
$ 90.00

Labseeker
4-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-1,3-OXAZOLE 95
10g
$ 2383.00

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-1,3-OXAZOLE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-1,3-OXAZOLE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
4-(CHLOROMETHYL)-2-(4-CHLOROPHENYL)-1,3-OXAZOLE 95.00%
1G
$ 852.55

AK Scientific
4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole
250mg
$ 248.00

Total 7 raw suppliers

Chemical Property of 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole

Chemical Property:

Vapor Pressure:0.0001mmHg at 25°C
Boiling Point:348.6°Cat760mmHg
Flash Point:164.6°C
PSA：26.03000
Density:1.338g/cm³
LogP:3.73380
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:226.9904692
Heavy Atom Count:14
Complexity:183

Purity/Quality:

98%min ^*data from raw suppliers

4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NC(=CO2)CCl)Cl

Technology Process of 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole

There total 5 articles about 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 22091-36-7
4-chloromethyl-2-(4-chlorophenyl)oxazole

Guidance literature:

Reference yield:

: 22087-22-5
[2-(4-chloro-phenyl)-oxazol-4-yl]-methanol

: 22091-36-7
4-chloromethyl-2-(4-chlorophenyl)oxazole

Guidance literature:: With thionyl chloride; In dichloromethane; for 2h; Reflux;
DOI:10.1016/j.bmcl.2015.09.072

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 22091-36-7
4-chloromethyl-2-(4-chlorophenyl)oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / ethyl acetate; water / 0.5 h / 0 °C

2: toluene / Reflux

With ammonium hydroxide; In water; ethyl acetate; toluene;
DOI:10.1021/jm401643m