diethyl 2-[(Z)-ethoxy(imino)methyl]-2-fluoropentanedioate

Base Information

• Chemical Name: diethyl 2-[(Z)-ethoxy(imino)methyl]-2-fluoropentanedioate
• CAS No.: 18283-09-5
• Molecular Formula: C₁₂H₂₀FNO₅
• Molecular Weight: 277.293
• Mol file: 18283-09-5.mol

Synonyms:Glutaricacid, 2-(1-ethoxyformimidoyl)-2-fluoro-, diethyl ester (8CI); NSC 81844

Chemical Property of diethyl 2-[(Z)-ethoxy(imino)methyl]-2-fluoropentanedioate

Chemical Property:

• Vapor Pressure: 0.000352mmHg at 25°C
• Boiling Point: 318.8°Cat760mmHg
• Flash Point: 146.6°C
• Density: 1.14g/cm³

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl 2-[(Z)-ethoxy(imino)methyl]-2-fluoropentanedioate

There total 1 articles about diethyl 2-[(Z)-ethoxy(imino)methyl]-2-fluoropentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2-cyanoglutarate (7251-97-0) + sodium ethanolate (141-52-6) → 2-Ethoxycarbonimidoyl-2-fluoro-pentanedioic acid diethyl ester (18283-09-5)

Guidance literature:

Multistep reaction; (i) EtOH, (ii) ClO₃F;

DOI:10.1021/jm00316a008

Reference yield:

2-Ethoxycarbonimidoyl-2-fluoro-pentanedioic acid diethyl ester (18283-09-5) → 2-Carbamoyl-2-fluoro-pentanedioic acid diamide (18491-25-3)

Guidance literature:

With ammonium hydroxide; In methanol;

DOI:10.1021/jm00316a008

upstream raw materials:

diethyl 2-cyanoglutarate

sodium ethanolate

Downstream raw materials:

2-Carbamoyl-2-fluoro-pentanedioic acid diamide