alpha,alpha-Diphenyl-2-quinuclidinemethanol

Base Information

Chemical Name:alpha,alpha-Diphenyl-2-quinuclidinemethanol
CAS No.:60999-40-8
Molecular Formula:C20H23NO
Molecular Weight:293.409
Hs Code.:
DSSTox Substance ID:DTXSID10976469
Nikkaji Number:J84.990A
ChEMBL ID:CHEMBL53262

Synonyms:BRN 0258680;alpha,alpha-Diphenyl-2-quinuclidinemethanol;Benzhydrol, alpha-(2-quinuclidinyl)-;2-Quinuclidinemethanol, alpha,alpha-diphenyl-;5-21-04-00173 (Beilstein Handbook Reference);60999-40-8;diphenylquinuclidinylmethanol;Oprea1_301983;CHEMBL53262;DTXSID10976469;STK382767;AKOS005451220;LS-143125;1-azabicyclo[2.2.2]oct-2-yl(diphenyl)methanol;(1-Azabicyclo[2.2.2]octan-2-yl)(diphenyl)methanol

Suppliers and Price of alpha,alpha-Diphenyl-2-quinuclidinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of alpha,alpha-Diphenyl-2-quinuclidinemethanol

Chemical Property:

Vapor Pressure:9.11E-09mmHg at 25°C
Boiling Point:446.8°Cat760mmHg
Flash Point:223.1°C
PSA：23.47000
Density:1.17g/cm³
LogP:3.34470
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:293.177964357
Heavy Atom Count:22
Complexity:344

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN2CCC1CC2C(C3=CC=CC=C3)(C4=CC=CC=C4)O

Technology Process of alpha,alpha-Diphenyl-2-quinuclidinemethanol

There total 5 articles about alpha,alpha-Diphenyl-2-quinuclidinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 112176-92-8,39926-11-9
(+/-)-ethyl quinuclidine-2-carboxylate

: 591-51-5
phenyllithium

: 72265-42-0
2-benzoylquinuclidine

: 60999-40-8
(1-aza-bicyclo[2.2.2]oct-2-yl)-diphenyl-methanol

Guidance literature:: In diethyl ether; benzene; for 0.166667h;
DOI:10.1021/jm00176a014

Reference yield:

: 52601-23-7,94160-98-2,52730-01-5
quinuiclidine-2-carboxylic acid hydrochloride

: 60999-40-8
(1-aza-bicyclo[2.2.2]oct-2-yl)-diphenyl-methanol

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / dimethylformamide / 24 h

2: 2 h / Heating

3: 21 percent / diethyl ether; benzene / 0.17 h

With thionyl chloride; In diethyl ether; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00176a014

Reference yield:

: 66073-49-2
quinuiclidine-2-carbonyl chloride hydrochloride

: 60999-40-8
(1-aza-bicyclo[2.2.2]oct-2-yl)-diphenyl-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / Heating

2: 21 percent / diethyl ether; benzene / 0.17 h

In diethyl ether; benzene;
DOI:10.1021/jm00176a014