4-BENZOYL-3-PHENYL-5-ISOXAZOLONE

Base Information

• Chemical Name: 4-BENZOYL-3-PHENYL-5-ISOXAZOLONE
• CAS No.: 41836-94-6
• Molecular Formula: C16H11NO3
• Molecular Weight: 265.26
• Hs Code.: 2934999090
• Mol file: 41836-94-6.mol

Synonyms:3-Phenyl-4-benzoyl-5-isoxazolone;HPBI,LAH;3-phenyl-4-benzoyl-isoxazol-5-one;4-benzoyl-3-phenyl-2H-isoxazol-5-one;3-Phenyl-4-benzoyl-isoxazolin-5-one;HPBI;

Chemical Property of 4-BENZOYL-3-PHENYL-5-ISOXAZOLONE

Chemical Property:

• Vapor Pressure: 7.91E-07mmHg at 25°C
• Melting Point: 148-152oC
• Boiling Point: 406.8°C at 760 mmHg
• Flash Point: 199.8°C
• PSA: 55.73000
• Density: 1.308g/cm³
• LogP: 1.88220

Purity/Quality:

98%Min ^*data from raw suppliers

4-BENZOYL-3-PHENYL-5-ISOXAZOLONE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-BENZOYL-3-PHENYL-5-ISOXAZOLONE

There total 5 articles about 4-BENZOYL-3-PHENYL-5-ISOXAZOLONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-oxo-3-phenylpropionate (94-02-0) + benzohydroximoyl chloride (698-16-8) → 3-phenyl-4-benzoyl-isoxazol-5-one (41836-94-6)

Guidance literature:

With sodium hydroxide; In diethyl ether;

Reference yield:

3-phenyl-4H-isoxazol-5-one (1076-59-1) + benzoic acid anhydride (93-97-0) → 3-phenyl-4-benzoyl-isoxazol-5-one (41836-94-6)

Guidance literature:

With sodium benzoate;

DOI:10.1016/0584-8539(87)80249-0

Reference yield:

4-(ethoxy-phenyl-methylene)-3-phenyl-4H-isoxazol-5-one (52835-79-7) → 3-phenyl-4-benzoyl-isoxazol-5-one (41836-94-6)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

ethyl 3-oxo-3-phenylpropionate

benzohydroximoyl chloride

4-(ethoxy-phenyl-methylene)-3-phenyl-4H-isoxazol-5-one

3-phenyl-4H-isoxazol-5-one

Downstream raw materials:

4-(diphenylmethylene)-3-phenylisoxazol-5(4H)-one

3,5-diphehylisoxazole

3,5-diphenyl-isoxazole-4-carboxylic acid