6-Methylquinoline-8-carboxylic acid

Base Information

Chemical Name:6-Methylquinoline-8-carboxylic acid
CAS No.:55706-57-5
Molecular Formula:C₁₁H₉NO₂
Molecular Weight:187.198
Hs Code.:2933499090
Mol file:55706-57-5.mol

Synonyms:6-Methyl-8-quinolinecarboxylic acid;6-methyl-quinoline-8-carboxylic acid;6-Methylchinolin-8-carbonsaeure;

Suppliers and Price of 6-Methylquinoline-8-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Methylquinoline-8-carboxylicacid 98%
250mg
$ 238.00

Crysdot
6-Methylquinoline-8-carboxylicacid 98%
1g
$ 594.00

Chemenu
6-Methylquinoline-8-carboxylicacid 98%
1g
$ 561.00

American Custom Chemicals Corporation
6-METHYLQUINOLINE-8-CARBOXYLIC ACID 95.00%
5MG
$ 504.06

Ambeed
6-Methylquinoline-8-carboxylicacid 98%
100mg
$ 144.00

Ambeed
6-Methylquinoline-8-carboxylicacid 98%
1g
$ 539.00

Ambeed
6-Methylquinoline-8-carboxylicacid 98%
250mg
$ 216.00

Alichem
6-Methylquinoline-8-carboxylicacid
250mg
$ 349.79

Alichem
6-Methylquinoline-8-carboxylicacid
100mg
$ 206.01

Alichem
6-Methylquinoline-8-carboxylicacid
1g
$ 849.25

Total 10 raw suppliers

Chemical Property of 6-Methylquinoline-8-carboxylic acid

Chemical Property:

Vapor Pressure:7.17E-07mmHg at 25°C
Melting Point:169 °C
Boiling Point:392.7°Cat760mmHg
PKA:-2.26±0.10(Predicted)
Flash Point:191.3°C
PSA：50.19000
Density:1.285g/cm³
LogP:2.24140
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

6-Methylquinoline-8-carboxylicacid 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-Methylquinoline-8-carboxylic acid

There total 5 articles about 6-Methylquinoline-8-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 84839-95-2
6-methyl-8-bromoquinoline

: 124-38-9,18923-20-1
carbon dioxide

: 55706-57-5
6-methylquinoline-8-carboxylic acid

Guidance literature:: 6-methyl-8-bromoquinoline; With tert.-butyl lithium; In diethyl ether; pentane; at -78 ℃; for 0.5h; Inert atmosphere;

carbon dioxide; In diethyl ether; pentane; Inert atmosphere;

With hydrogenchloride; In water; Inert atmosphere;
DOI:10.1021/acs.joc.6b03011

Reference yield:

2-bromo-p-toluidine: 583-68-6
2-bromo-p-toluidine

: 55706-57-5
6-methylquinoline-8-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: ferrous(II) sulfate heptahydrate; sodium 3-nitrobenzenesulfonate; methanesulfonic acid / Inert atmosphere

2.1: tert.-butyl lithium / diethyl ether; pentane / 0.5 h / -78 °C / Inert atmosphere

2.2: Inert atmosphere

2.3: Inert atmosphere

With ferrous(II) sulfate heptahydrate; methanesulfonic acid; tert.-butyl lithium; sodium 3-nitrobenzenesulfonate; In diethyl ether; pentane; 1.1: |Skraup Quinoline Synthesis;
DOI:10.1021/acs.joc.6b03011