84839-95-2 Usage
General Description
8-Bromo-6-methylquinoline is a chemical compound with the molecular formula C10H8BrN. It is a derivative of quinoline, which is a heterocyclic aromatic compound commonly found in coal tar. The compound contains a bromine atom attached to the eighth carbon of the quinoline ring and a methyl group attached to the sixth carbon. 8-Bromo-6-methylquinoline is mainly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It possesses antimicrobial, anti-inflammatory, and analgesic properties, making it a potentially valuable compound in the development of new drugs. Its structural and pharmacological properties make it an important intermediate in the production of various bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 84839-95-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,8,3 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 84839-95:
(7*8)+(6*4)+(5*8)+(4*3)+(3*9)+(2*9)+(1*5)=182
182 % 10 = 2
So 84839-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H8BrN/c1-7-5-8-3-2-4-12-10(8)9(11)6-7/h2-6H,1H3
84839-95-2Relevant articles and documents
Catalytic dehydrogenative borylation of terminal alkynes by a SiNN pincer complex of iridium
Lee, Chun-I,Zhou, Jia,Ozerov, Oleg V.
, p. 3560 - 3566 (2013/04/23)
Compounds with carbon-boron bonds are versatile intermediates for building more complex molecules via the elaboration of the carbon-boron bonds into other carbon-element bonds. The synthesis of carbon-boron bonds by catalytic dehydrogenative borylation of carbon-hydrogen bonds with dialkoxyboranes (RO)2BH is particularly attractive. It has been demonstrated for a variety of carbon-hydrogen bond types but not for the C(sp)-H bonds of terminal alkynes, for which hydroboration of the triple bond is a competing process. We report a new iridium catalyst that is strictly chemoselective for C-H borylation of terminal alkynes. The key to the success of this catalyst appears to be the new ancillary SiNN pincer ligand that combines amido, quinoline, and silyl donors and gives rise to structurally unusual Ir complexes. A variety of terminal alkynes (RC≡C-H) can be converted to their alkynylboronates (RC≡C-Bpin, where pin = pinacolate) in high yield and purity within minutes at ambient temperature.
