4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile

Base Information

Chemical Name:4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
CAS No.:97749-21-8
Molecular Formula:C₂₉H₃₀N₄O₂
Molecular Weight:466.583
Hs Code.:
UNII:IO61JQ0O8I
Nikkaji Number:J22.173B
Mol file:97749-21-8.mol

Synonyms:97749-21-8;IO61JQ0O8I;UNII-IO61JQ0O8I;DPI-205-430;S-(-)-Dpi 201-106;DPI-201-106, (S)-;4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile;1H-Indole-2-carbonitrile, 4-((2S)-3-(4-(diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-;DPI-201106;SCHEMBL5332961;4-[(2S)-3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy]-1H-indole-2-carbonitrile

Suppliers and Price of 4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile

Chemical Property:

PSA：75.52000
LogP:4.06228
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:466.23687621
Heavy Atom Count:35
Complexity:672

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CC(COC2=CC=CC3=C2C=C(N3)C#N)O)C(C4=CC=CC=C4)C5=CC=CC=C5
Isomeric SMILES:C1CN(CCN1C[C@@H](COC2=CC=CC3=C2C=C(N3)C#N)O)C(C4=CC=CC=C4)C5=CC=CC=C5

Technology Process of 4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile

There total 2 articles about 4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 841-77-0
diphenylmethylpiperazine

: 73907-82-1
4-(2,3-epoxypropoxy)-1H-indol-2-carbonitrile

: 97730-95-5,97749-21-8
DPI 201-106

Guidance literature:: With malonic acid; In methanol; ethanol;

Reference yield:

: 841-77-0
diphenylmethylpiperazine

: 556-52-5
oxiranyl-methanol

: 106469-57-2
4-hydroxy-1H-indole-2-carbonitrile

: 97730-95-5,97749-21-8
DPI 201-106

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; Yield given. Multistep reaction; 1.) THF, RT, 6 h, 2.) acetone, 80 deg C, 15 min;
DOI:10.1080/00397919508011384